On-line control of glucose concentration using an automatic glucose analyzer

Glucose Transforming Enzymes

“…Automatic glucose analysers using glucose sensors were developed e.g. for fermentation process monitoring (Mizutani et al, 1987). Immobilized GOD packed in small columns may be used in flow injection analysis of glucose.…”

Control of acetic acid concentration by pH-stat continuous substrate feeding in heterotrophic culture phase of two-stage cultivation ofAlcaligenes eutrophus for production of P(3HB) from CO2, H2, and O2 under non-explosive conditions

“…In recent years, an on-line enzymatic glucose analyzer has often been used for control of glucose concentration. This analyzer enables control of glucose concentration at very low levels below 0.08 g и dm −3 (Mizutani et al, 1987). Kim et al reported that the use of an on-line glucose sensor could give 164 g и dm −3 of cells and 121 g и dm −3 of P(3HB) after 50 h of cultivation of A. eutrophus (Kim et al, 1994).…”

Application of fuzzy reasoning to control of glucose and ethanol concentrations in baker's yeast culture

“…We have investigated the control of glucose concentration at low values in various bioprocesses (Mizutani et al 1987;Lin et al 1989Lin et al , 1991. In recombinant yeast cultivation, inducible promoters were used to obtain an effective production of cloned gene product.…”

“…In recent years many researchers have developed biosensors to measure the concentrations of carbon and nitrogen sources, and metabolites on-or off-line. Among them an automatic glucose analyser was developed to measure glucose concentration in culture broth on-line by a biosensor, and it was applied to control glucose concentration for yeast cultivation (Mizutani et al 1987).…”