We study the asymptotic expansion for the Landau constants G n ,where N = n + 1, and γ is Euler's constant. We show that the signs of the coefficients α k demonstrate a periodic behavior such that (−1)for all n = 0, 1, 2 · · · , all p = 4s + 1, 4s + 2 and q = 4m, 4m + 3, with s = 0, 1, 2, · · · and m = 0, 1, 2, · · · .