“…Motivated by this, recently, a new class of economic model predictive control systems (EMPC), in which the cost function penalizes process economics instead of the distances from the steady-state in a general quadratic form, was utilized to account for process operational safety and economic optimality based on a function called the Safeness Index [2,3]. These new EMPC methods complement previous efforts on economic model predictive control (e.g., [4][5][6][7]), which were not concerned explicitly with process operational safety. Specifically, in [2], a Safeness Index function that indicates the level of safety of a given state was utilized to characterize a safe operating region and used as a constraint in the EMPC design such that the closed-loop state of a nonlinear process is guaranteed to be driven into the safe operating region in finite time in the presence of sufficiently small bounded disturbances and, if the Safeness Index takes a special form related to a Lyapunov function used in the EMPC design, to never again exit that safe operating region while maximizing the economics of the process.…”