On a “sympathetic” component in the afferent innervation of trunk dermatomes

Harreveld, A. Van; Smith, Hugh P.

doi:10.1152/jn.1952.15.4.313

Cited by 7 publications

(3 citation statements)

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“…The present findings allow an alternative interpretation of the evidence put forward by van Harreveld & Smith (1952). The areas of residual sensation which they found were dependent upon the continuity of the sympathetic chain may have depended, not on the chain as such, but upon the demonstrated pathways from the chest wall into the rami.…”

Section: Discussionsupporting

confidence: 65%

“…In one of his illustrated dissections of sympathetic chains of the dog Gaskell (1886), however, shows a branch from a ramus leading off to the body wall. More recently van Harreveld & Smith (1952) have found small residual areas of sensation in the skin of the trunk after spinal nerve section beyond the origins of the rami; these areas are dependent on afferent fibres which somehow traverse the sympathetic chain, and have a strictly segmental distribution from 10th thoracic to 4th lumbar inclusive. Studying the afferent connexions of the stellate ganglion, Holmes & Torrance (1959) found that proprioceptive afferents from longus colli muscle pass through the ganglion to the upper four thoracic white SOMATIC PATHS IN RAMI COMMUNICANTES rami on their way to the cord.…”

mentioning

confidence: 99%

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Somatic nerve pathways through some thoracic rami communicantes

Downman¹,

Hazarika²

1962

The Journal of Physiology

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Section: Discussionsupporting

confidence: 65%

mentioning

confidence: 99%

Somatic nerve pathways through some thoracic rami communicantes

Downman¹,

Hazarika²

1962

The Journal of Physiology

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“…However, peripheral nerve injury may activate biochemical states in muscle similar to those in developing muscle. For example, denervated muscle or muscle functionally denervated by botulinum toxin, exhibited greatly enhanced neuronal sprouting activity and synapse formation (Pestronk and Drachman, 1978;van Harreveld and Smith, 1952;Hoffman, 1950).…”

Section: Introductionmentioning

confidence: 99%

Insulin‐like growth factors: Putative muscle‐derived trophic agents that promote motoneuron survival

Neff¹,

et al. 1993

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Treatment of chick embryos in ovo with IGF-I during the period of normal, developmentally regulated neuronal death (embryonic days 5-10) resulted in a dose-dependent rescue of a significant number of lumbar motoneurons from degeneration and death. IGF-II and two variants of IGF-I with reduced affinity for IGF binding proteins, des(1-3) IGF-I and long R3 IGF-I, also elicited enhanced survival of motoneurons equal to that seen in IGF-I-treated embryos. IGF-I did not enhance mitogenic activity in motoneuronal populations when applied to embryos during the period of normal neuronal proliferation (E2-5). Treatment of embryos with IGF-I also reduced two types of injury-induced neuronal death. Following either deafferentation or axotomy, treatment of embryos with IGF-I rescued approximately 75% and 50%, respectively, of the motoneurons that die in control embryos as a result of these procedures. Consistent with the survival-promoting activity on motoneurons in ovo, IGF-I, -II, and des(1-3) IGF-I elevated choline acetyltransferase activity in embryonic rat spinal cord cultures, with des(1-3) IGF-I demonstrating 2.5 times greater potency than did IGF-I. A single addition of IGF-I at culture initiation resulted in the maintenance of 80% of the initial ChAT activity for up to 5 days, during which time ChAT activity in untreated control cultures fell to 9%. In summary, these results demonstrate clear motoneuronal trophic activity for the IGFs. These findings, together with previous reports that IGFs are synthesized in muscle and may participate in motoneuron axonal regeneration and sprouting, indicate that these growth factors may have an important role in motoneuron development, maintenance, and recovery from injury.

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