On a dark-field signal generated by micrometer-sized calcifications in phase-contrast mammography

Michel, Thilo; Rieger, Jens; Anton, G.; Bayer, Florian; Beckmann, Matthias W.; Durst, Jürgen; Fasching, Peter A.; Haas, Wilhelm; Hartmann, Arndt; Pelzer, Georg; Radicke, Marcus; Rauh, Claudia; Ritter, André; Sievers, P.; Schulz‐Wendtland, Rüdiger; Uder, Michael; Wachter, David; Weber, Thomas; Wenkel, Evelyn; Zang, Andrea

doi:10.1088/0031-9155/58/8/2713

Cited by 124 publications

(116 citation statements)

References 24 publications

Supporting

Mentioning

110

Contrasting

Order By: Relevance

“…This is the case e.g. in radiography or mammography [4,5,8,9], where deconvolution information retrieval can reduce the necessary dose for a predefined image quality.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Increasing the darkfield contrast-to-noise ratio using a deconvolution-based information retrieval algorithm in X-ray grating-based phase-contrast imaging

Weber¹,

Pelzer²,

Bayer³

et al. 2013

Opt. Express

Self Cite

View full text Add to dashboard Cite

A novel information retrieval algorithm for X-ray grating-based phase-contrast imaging based on the deconvolution of the object and the reference phase stepping curve (PSC) as proposed by Modregger et al. was investigated in this paper. We applied the method for the first time on data obtained with a polychromatic spectrum and compared the results to those, received by applying the commonly used method, based on a Fourier analysis. We confirmed the expectation, that both methods deliver the same results for the absorption and the differential phase image. For the darkfield image, a mean contrast-to-noise ratio (CNR) increase by a factor of 1.17 using the new method was found. Furthermore, the dose saving potential was estimated for the deconvolution method experimentally. It is found, that for the conventional method a dose which is higher by a factor of 1.66 is needed to obtain a similar CNR value compared to the novel method. A further analysis of the data revealed, that the improvement in CNR and dose efficiency is due to the superior background noise properties of the deconvolution method, but at the cost of comparability between measurements at different applied dose values, as the mean value becomes dependent on the photon statistics used.

show abstract

“…This is the case e.g. in radiography or mammography [4,5,8,9], where deconvolution information retrieval can reduce the necessary dose for a predefined image quality.…”

Section: Resultsmentioning

confidence: 99%

“…Especially the dark field image shows promising results e.g. in the detection of super-fine micro-calcifications not seen by conventional attenuation-based mammography [8,9].…”

Section: Introductionmentioning

confidence: 99%

Increasing the darkfield contrast-to-noise ratio using a deconvolution-based information retrieval algorithm in X-ray grating-based phase-contrast imaging

Weber¹,

Pelzer²,

Bayer³

et al. 2013

Opt. Express

Self Cite

View full text Add to dashboard Cite

show abstract

“…These two techniques work with conventional x-ray sources and can be adapted to existing medical imaging systems [6]. Several groups have shown promising results for medical imaging applications [7][8][9][10][11] as well as for non-destructive testing [12][13][14][15][16]. For quality assessment of a Talbot-Lau interferometer, the visibility is a crucial quantity.…”

Section: Introductionmentioning

confidence: 99%

Designing the phase grating for Talbot-Lau phase-contrast imaging systems: a simulation and experiment study

et al. 2016

Self Cite

View full text Add to dashboard Cite

Abstract:The performance of a Talbot-Lau interferometer depends to a great extent on its visibility. This means, to obtain high quality phase-contrast and dark-field images a high visibility is mandatory. Several parameters influence the visibility of such a system, like for example the x-ray spectrum, the inter-grating distances or the parameters of the three gratings. In this multidimensional space, wave field simulations help to find the optimal combination of the grating specifications to construct a setup with a high visibility while retaining a fixed angular sensitivity. In this work we specifically analyzed the influence of the G1 grating duty cycle in simulations and experiments. We show that there is a lot of room for improvement by varying the duty cycle of the phase-shifting grating G1. As a result, by employing a third-integer duty cycle we can increase the visibility to up to 53 % in a laboratory setup with a polychromatic spectrum. The achieved visibility is more than two times higher compared to the result with a standard-type setup. This visibility gain allows a dose reduction by a factor of 5 preserving the same image quality. "Energy-resolved visibility analysis of grating interferometers operated at polychromatic X-ray sources," Opt.

show abstract

“…in lung imaging [9][10][11] and mammography [12] -, can be obtained within a single scan using a grating interferometer (GI, Fig. 1) [2].…”

Section: Introductionmentioning

confidence: 99%

Fast one-dimensional wave-front propagation for x-ray differential phase-contrast imaging

Wolf¹,

Malecki²,

Sperl³

et al. 2014

Biomed. Opt. Express

View full text Add to dashboard Cite

Abstract:Numerical wave-optical simulations of X-ray differential phase-contrast imaging using grating interferometry require the oversampling of gratings and object structures in the range of few micrometers. Consequently, fields of view of few millimeters already use large amounts of a computer's main memory to store the propagating wave front, limiting the scope of the investigations to only small-scale problems. In this study, we apply an approximation to the Fresnel-Kirchhoff diffraction theory to overcome these restrictions by dividing the two-dimensional wave front up into 1D lines, which are processed separately. The approach enables simulations with samples of clinically relevant dimensions by significantly reducing the memory footprint and the execution time and, thus, allows the qualitative comparison of different setup configurations. We analyze advantages as well as limitations and present the simulation of a virtual mammography phantom of several centimeters of size. Reiser, and F. Bamberg, "Assessment of grating-based X-ray phase-contrast CT for differentiation of invasive ductal carcinoma and ductal carcinoma in situ in an experimental ex vivo set-up." Eur. Radiol. 2, 381-387 (2012). 9. F. Pfeiffer, M. Bech, O. Bunk, P. Kraft, E. F. Eikenberry, C. Bronnimann, C. Grünzweig, and C. David, "Hard-xray dark-field imaging using a grating interferometer," Nat. Mater. 7, 134-137 (2008

show abstract

On a dark-field signal generated by micrometer-sized calcifications in phase-contrast mammography

Cited by 124 publications

References 24 publications

Increasing the darkfield contrast-to-noise ratio using a deconvolution-based information retrieval algorithm in X-ray grating-based phase-contrast imaging

Increasing the darkfield contrast-to-noise ratio using a deconvolution-based information retrieval algorithm in X-ray grating-based phase-contrast imaging

Designing the phase grating for Talbot-Lau phase-contrast imaging systems: a simulation and experiment study

Fast one-dimensional wave-front propagation for x-ray differential phase-contrast imaging

Contact Info

Product

Resources

About