Ominous lung cavity “Tambourine sign”

Verma, Ritu; Bhalla, Ashu Seith; Goyal, Ankur; Jain, Deepali; Loganathan, N; Guleria, Randeep

doi:10.12998/wjcc.v5.i4.153

Cited by 3 publications

(4 citation statements)

References 13 publications

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“…One such report had similar CT evidence of patchy airspace consolidations with cavitations and was also initially thought to be infectious in origin and treated with antibiotic therapy [ 8 ]. CT imaging in two other cases revealed multiple cavitary lesions similar to our present case [ 9 , 10 ]. Another report described CT findings of a single cavitary lesion, later pathologically confirmed as adenocarcinoma [ 11 ].…”

Section: Discussionsupporting

confidence: 84%

An Unusual Case of Mucinous Adenocarcinoma of the Lung Presenting as Septic Emboli

DEMARS¹,

Khan²,

LeBel³

et al. 2023

Cureus

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This is a case of a 92-year-old female with multiple hospitalizations for dyspnea on exertion and hypoxemia. Her symptoms were initially thought to be secondary to pneumonia, and on subsequent admission, culture-negative endocarditis. A computed tomography (CT) of the chest was remarkable for numerous bilateral lung nodules of varying size, some of which had a cavitary appearance raising concern for septic emboli. While a transthoracic echo was unremarkable, a transesophageal echo found a small 3 mm echodensity at the tip of the right coronary leaflet of the aortic valve and a possible mobile echodensity on the tricuspid valve leaflet. These findings further supported a clinical diagnosis of endocarditis with septic emboli in the lungs. Initial bronchoscopy yielded an unremarkable biopsy and a bronchial alveolar lavage with the growth of Actinomyces odontolyticus . During a subsequent hospitalization, a repeat bronchoscopy with transbronchial biopsy revealed a final diagnosis of invasive pulmonary mucinous adenocarcinoma. This case highlights a unique presentation of mucinous adenocarcinoma of the lung initially masquerading as septic emboli, resulting in a delay in the final diagnosis.

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Section: Discussionsupporting

confidence: 84%

An Unusual Case of Mucinous Adenocarcinoma of the Lung Presenting as Septic Emboli

DEMARS¹,

Khan²,

LeBel³

et al. 2023

Cureus

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“…Multiple cavitary lesions in the lung can be observed in many diseases such as tuberculosis, nontuberculous mycobacterial infection, and primary or metastatic lung cancer [ 8 ]. To the best of our knowledge, there are a few case reports of IMAs with cavities [ 2 , 3 ]. It has been reported that 7-13% of IMAs are accompanied by a cavity, and cavitary IMA tends to have a poor prognosis compared with noncavitary IMA [ 9 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…Invasive mucinous adenocarcinoma (IMA), formerly classified as mucinous bronchioloalveolar carcinoma, is a variant of adenocarcinoma according to the International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society lung adenocarcinoma classification system [ 1 ]. The typical computed tomography (CT) finding of IMA is multiple consolidations or ground-glass opacities mimicking pneumonia; however, there are a few reports of IMA with cavitary lesions [ 2 , 3 ]. Here, we report a case of IMA with multiple lung cavities.…”

Section: Introductionmentioning

confidence: 99%

Invasive Mucinous Adenocarcinoma of the Lung Presenting With Multiple Cavities

Nakamura¹,

Sugimoto²,

Negoro³

et al. 2021

Cureus

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A 78-year-old woman presented to our hospital with a two-week history of productive cough. Chest computed tomography (CT) showed bilateral multiple pulmonary nodules with cavities. Although the cytology of her sputum revealed adenocarcinoma, she refused any treatment. Following supportive care, 30 months later, she presented to our hospital with dyspnea and fever. Chest CT showed progression of multiple pulmonary nodules and cavities. Despite treatment with antibiotics and palliative care, she died on the 10th day of hospitalization. Pathological autopsy confirmed the diagnosis of pulmonary invasive mucinous adenocarcinoma (IMA). The typical CT findings of IMA include multiple consolidations or ground-glass opacities mimicking pneumonia; rarely, cavitary lesions are also observed. Clinicians should consider IMA as a differential diagnosis for lung cavities.

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“…We report a case of IMA with confluent cavitary lesions in the lung following the guidelines of the CARE guide for case reports [6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Confluent cavitated nodules in invasive mucinous adenocarcinoma: A case report

et al. 2023

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Invasive mucinous adenocarcinoma is a rare variant of lung adenocarcinoma. Here, we present the case of a patient with invasive mucinous adenocarcinoma with cavitary lung lesions. A 61-year-old painter-and-bricklayer. She was admitted due to mMRC2 dyspnea, a dry cough that during hospitalization mobilizes dense, abundant secretions, and becomes demanding. Differential diagnoses were made based on clinical symptoms and images, performing multiple laboratory tests ruling out immunosuppression, and two video-bronchofibroscopies finding the diagnosis in the transbronchial lung biopsy: Invasive mucinous adenocarcinoma that would explain the abundant bronchorrhea, advanced stage and poor prognosis led to ventilatory failure and death of the patient.

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Ominous lung cavity “Tambourine sign”

Cited by 3 publications

References 13 publications

An Unusual Case of Mucinous Adenocarcinoma of the Lung Presenting as Septic Emboli

An Unusual Case of Mucinous Adenocarcinoma of the Lung Presenting as Septic Emboli

Invasive Mucinous Adenocarcinoma of the Lung Presenting With Multiple Cavities

Confluent cavitated nodules in invasive mucinous adenocarcinoma: A case report

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