Olopatadine hydrochloride ophthalmic solution for the treatment of allergic conjunctivitis

Abstract

Olopatadine hydrochloride is an antihistamine and mast cell stabilizer available as oral, intranasal and ocular preparations. Most of the practical applications of olopatadine therapy focus on the treatment of allergic rhinoconjunctivitis via intranasal and ocular routes. Areas covered: This article was created from a comprehensive literature search with information taken from meta-analyses, systematic reviews, and clinical trials of children and adults. The articles that have been selected, evaluate the use of intranasal and ocular antihistamines and their role in allergic rhinoconjunctivitis. Expert opinion: Olopatadine is significantly more effective than placebos in relieving the symptoms of allergic rhinoconjunctivitis. It can function both as a viable alternative or addition to first line therapies such as intranasal steroids and oral antihistamines.

Green and sensitive detection of olopatadine in aqueous humor using a signal‐on fluorimetric approach: GREEnness assessment

“…Olopatadine ((Z)-11-[(3-dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid hydrochloride, Figure S1) is a medication used to treat allergic reactions in the eyes. It belongs to a group of drugs called antihistamines, which act by impairing the impacts of histamine, a biomolecule in the body that causes allergic symptoms [18,19]. This drug comes in the form of eye drops and is commonly prescribed to relieve symptoms such as itching, redness, and watering of the eyes caused by allergies like hay fever or allergic conjunctivitis [20][21][22].…”