Olive Trees By-Products as Sources of Bioactive and Other Industrially Useful Compounds: A Systematic Review

Giudice, Valentina Lo; Faraone, Immacolata; Bruno, Maria Roberta; Ponticelli, Maria; Labanca, Fabiana; Bisaccia, Donatella; Massarelli, Carmine; Milella, Luigi; Todaro, Luigi

doi:10.3390/molecules26165081

Cited by 14 publications

(4 citation statements)

References 113 publications

(154 reference statements)

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“…ROS are also the major responsible for lipid-containing food degradation, which makes it necessary to add synthetic antioxidants to food. However, in the last years, several investigations demonstrated that synthetic antioxidants generally used by food industries, such as butylated hydroxytoluene (BHT), tert-butylhydeoquinone (TBHQ), and butylated hydroxyanisole (BHA), are not without side effects for human health [ 24 ]. For this reason, the research of a new safe antioxidant from natural origin is demanded.…”

Section: Discussionmentioning

confidence: 99%

Harnessing Cyanobacteria’s Bioactive Potential: A Sustainable Strategy for Antioxidant Production

De Rosa,

Ponticelli,

Teta

et al. 2024

Microorganisms

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Unsaturated diacylglycerols are a class of antioxidant compounds with the potential to positively impact human health. Their ability to combat oxidative stress through radical scavenger activity underscores their significance in the context of preventive and therapeutic strategies. In this paper we highlight the role of Anabaena flos-aquae as a producer of unsaturated mono and diacylglycerols, and then demonstrate the antioxidant activity of its methanolic extract, which has as its main components a variety of acylglycerol analogues. This finding was revealed using a sustainable strategy in which the One Strain Many Compounds (OSMAC) cultivation in microscale was coupled with a bioinformatic approach to analyze a large dataset of mass spectrometry data using the molecular networking analyses. This strategy reduces time and costs, avoiding long and expensive steps of purification and obtaining informative data on the metabolic composition of the extracts. This study highlights the role of Anabaena as a sustainable and green source of novel bioactive compounds.

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Section: Discussionmentioning

confidence: 99%

Harnessing Cyanobacteria’s Bioactive Potential: A Sustainable Strategy for Antioxidant Production

De Rosa,

Ponticelli,

Teta

et al. 2024

Microorganisms

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“…The peak numbers 6-8 present several similarities with oleuropein and oleuropein derivatives, such as dihydro-oleuropein and oleuropein aglycone. These compounds were detected in several olive fruit by-products [54][55][56], since they are a degrading form of olive fruits' secoiridoids, i.e., oleuropein and dimethyloleuropein, which occur during crushing/malaxation, thus forming several secoiridoid aglycone derivatives [25,57]. Moreover, fruit flavonoids such as luteolin-7-O-glucoside and rutin, as well as cinnamic acid esters such as verbascoside and comselogoside, have been reported in fruit derivatives (paste, pomace, and wastewater) [25], indicating their preferred transfer to waste without many alterations.…”

Section: Identification Of Phenolic Compoundsmentioning

confidence: 99%

The Recovery of Bioactive Compounds from Olive Pomace Using Green Extraction Processes

et al. 2023

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In this study, solid olive mill waste (SOMW) was used to obtain antioxidant compounds using solid–liquid extraction. The effect of different extraction methods, namely microwave-assisted extraction (MAE), ultrasound-assisted extraction (UAE), Soxhlet, and conventional solvent extraction, on the yield, total phenolics, and total antioxidant activity of SOMW extracts was investigated. Untreated and dried SOMW were subjected to extraction with water and methanol. The antioxidant activity of the extracts was evaluated using the DPPH assay, while their total phenolic content was measured using the Folin–Ciocalteu method. For the characterisation of the extracts, HPLC-DAD analysis was performed. The results showed that the extraction yield was significantly influenced (p < 0.05) by the solvent used, the material treatment prior to extraction, the moisture content of SOMW samples, and the extraction time. The optimised parameters were water, as the extraction solvent, and MAE as the extraction technique (extraction temperature of 50 °C and time of 1 h). The evaluation of the antioxidant activity of the extracts indicated that phenolics were the dominant bioactive compounds. The extracts were found to be rich in several hydroxytyrosol derivatives. Therefore, SOMW can be a valuable resource for bioactive compounds using conventional and innovative extraction techniques.

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“…Significant medical benefits are provided by the leaves, fruits, and oil. When infused or decocted, the leaves help regulate type II diabetes, decrease moderate hypertension, promote urine elimination, and protect against viral, bacterial, or fungal infections (Lo Giudice et al, 2021).…”

Section: Olive Tree Categories In Tunisiamentioning

confidence: 99%

Bioactive chemlali olive derivatives and compounds useful for pharmaceutical purposes: A review

Ksibi

2023

ijpbp

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Several articles in the literature deal with and analyze components extracted from the olive tree, but these researches are mainly focused on the quality of olive oil and more precisely its volatile components, often related to their antioxidant properties, which denies other derivatives of the olive tree that are traditional sources of several healing broths. A thorough comparison of the richness of the different derivatives as well as the methods of extraction and identification will help to provide a useful decision-making tool. Olive tree derivatives were extracted in different ways to better understand the chemical composition of the Chemlali olive tree variety as well as to evaluate the efficiency of advanced extraction procedures. A comparison through the IC50 of the Chemlali variety with other olive cultivars was performed. It shows the richness of this variety in polyphenols. In addition, we present here a qualitative and quantitative table of basic chemicals for pharmacological use derived from olive oil, leaf, and bark that have been previously described in the literature. Diverse types and concentrations of phenolic compounds-an important class of natural antioxidants-can be found in different components of olives, including leaves, fruit, pits, seeds, bark, and paste. However, comprehensive studies are deficient in comparing the quantities extracted from these different sources. Indeed, this review attempt shows the diversity of Chemlali through the use of highvalue-added molecules (VAT), which can be categorized as diterpenes such as tyrosol and phytol, triterpenes such as squalene, as well as cinnamates.

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Olive Trees By-Products as Sources of Bioactive and Other Industrially Useful Compounds: A Systematic Review

Cited by 14 publications

References 113 publications

Harnessing Cyanobacteria’s Bioactive Potential: A Sustainable Strategy for Antioxidant Production

Harnessing Cyanobacteria’s Bioactive Potential: A Sustainable Strategy for Antioxidant Production

The Recovery of Bioactive Compounds from Olive Pomace Using Green Extraction Processes

Bioactive chemlali olive derivatives and compounds useful for pharmaceutical purposes: A review

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