Olive oil lessened fatty liver severity independent of cardiometabolic correction in patients with non-alcoholic fatty liver disease: A randomized clinical trial

Rezaei, Shahla; Akhlaghi, Masoumeh; Sasani, Mohammad Reza; Barati‐Boldaji, Reza

doi:10.1016/j.nut.2018.02.021

Cited by 62 publications

(80 citation statements)

References 40 publications

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“…22 In a randomized, double-blind clinical trial, the consumption of 20 g/d of olive oil attenuated the fatty liver grade in NAFLD patients. 7 Finally, a randomized trial in prediabetic patients with an isocaloric diet rich in EVOO, reported a decrease in liver fat and an improvement in both hepatic and total insulin sensitivity. 23 Because people consume different amounts of various food groups and because of the limited number of large clinical trials, in some cases the impact of different foods are not clear, for example dairy products, coffee and rice.…”

Section: Relationship Between Food Group Intake and Non-alcoholic Fmentioning

confidence: 99%

“…In addition, the consumption of 20 g/day for 12 weeks in hypocaloric diets attenuated the degree of fatty liver in patients with NAFLD. However, it is difficult to isolate the effects of MUFA from other components (polyphenols), present in EVOO and the importance of the hypocaloric diet …”

Section: Influence Of Dietary Macronutrients On Non‐alcoholic Fatty Lmentioning

confidence: 99%

“…It has been suggested that EVOO should be included in the diets of NAFLD patients since it reduces insulin resistance and blood triglycerides, thus inducing downregulation of lipogenic genes . In a randomized, double‐blind clinical trial, the consumption of 20 g/d of olive oil attenuated the fatty liver grade in NAFLD patients . Finally, a randomized trial in prediabetic patients with an isocaloric diet rich in EVOO, reported a decrease in liver fat and an improvement in both hepatic and total insulin sensitivity …”

Section: From Major Foods Groups To Dietary Patterns: Evidence From Nmentioning

confidence: 99%

“…However, it is difficult to isolate the effects of MUFA from other components (polyphenols), present in EVOO and the importance of the hypocaloric diet. 7 Polyunsaturateds, including mainly ω3 and ω6 fats have also been evaluated in the progression of NAFLD in particular the essential PUFAS, α-linolenic acid (ALA; ω3) and linoleic acid (LA; ω6). LA is metabolized to arachidonic acid (AA; 20:4 n-6), and ALA is metab- Therefore, the ratio ω6/ω3 fats plays an important role in increasing the prevalence of chronic metabolic diseases (mostly a ω6/ω3 imbalance).…”

Section: The Role Of Fatsmentioning

confidence: 99%

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The role of nutrition in non‐alcoholic fatty liver disease: Pathophysiology and management

Berná

Romero–Gómez

2020

Liver International

157

130

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A healthy diet together with physical activity could induce weight loss and control the progression of non‐alcoholic fatty liver disease (NAFLD). However, the composition of diet has not been clearly established. Macronutrients such as saturated fatty acids (SFA), trans‐fats, simple sugars and animal proteins have a harmful effect on the liver. On the other hand, monounsaturated fats (MUFAs), polyunsaturated (PUFAs) omega‐3‐fats, plant‐based proteins and dietary fibres are considered to be beneficial to the liver. The impact of specific micronutrients is less well‐known. Nutrients are part of the food we eat. Food makes up our meals, which compose our dietary patterns. Non‐alcoholic fatty liver disease patients usually follow Western diets which are rich in soda, frozen junk food, juice, red meat, lard, processed meats, whole fat dairy foods, fatty snack foods, take‐away foods, cakes and biscuits and poor in cereals, whole grains, fruit, vegetables, extra virgin olive oil (EVOO) and fish. On the other hand, the Mediterranean diet (MD) is beneficial for NAFLD even when it is iso‐caloric or there are no changes in body weight. A new approach, called ‘nutritional geometry’ considers the importance of integrating nutrition, animals and the environment. The goal of this approach is to combine nutrients and foods in a model to understand how food components interact to regulate the properties of diets affecting health and disease. The use of algorithms developed by artificial intelligence (AI) to create a personalized diet for patients can provide customized nutritional counselling to prevent and treat NAFLD.

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Section: Relationship Between Food Group Intake and Non-alcoholic Fmentioning

confidence: 99%

Section: Influence Of Dietary Macronutrients On Non‐alcoholic Fatty Lmentioning

confidence: 99%

Section: From Major Foods Groups To Dietary Patterns: Evidence From Nmentioning

confidence: 99%

Section: The Role Of Fatsmentioning

confidence: 99%

See 2 more Smart Citations

The role of nutrition in non‐alcoholic fatty liver disease: Pathophysiology and management

Berná

Romero–Gómez

2020

Liver International

157

130

View full text Add to dashboard Cite

show abstract

“…The study related to the effectiveness of olive oil on cardiometabolic markers and severity of fatty liver was conducted by Rezaei S et al 2018. 57 It was a double-blind, randomized control trial involving 66 patients with NAFLD. Patients were alienated into 2 categories and advised to consume either olive oil or sunflower oil each 20g/day for 1 month.…”

Section: G Study Reports Related To Treatment Of Nafldmentioning

confidence: 99%

A Recent Research on Non Alcoholic Fatty Liver Disease

2019

IJRTE

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Non alcoholic fatty liver disease (NAFLD) is a persistent condition of liver steatosis in the absence of alcohol consumption. The main risk factors associated with the disease are hypertension, diabetes mellitus and dyslipidemia these are together termed as metabolic syndrome. Recent studies identified that children are more vulnerable to develop NAFLD in future due to sedentary life styles and poor diet. NAFLD can further make complications of cardiovascular and liver related disorders. Apart from these causes there are factors such as enzyme, gene expression; amino acid regulation and so on in the human body plays an important role in the development of NAFLD. The objective of this research is to summaries the various ways by which a NAFLD is affected in a normal individual and to point out current research on treatment strategy for the NAFLD.

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Lifestyle modifications for nonalcohol-related fatty liver disease: a network meta-analysis

Buzzetti

Linden

Best

et al. 2021

Cochrane Database of Systematic Reviews

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Olive oil lessened fatty liver severity independent of cardiometabolic correction in patients with non-alcoholic fatty liver disease: A randomized clinical trial

Cited by 62 publications

References 40 publications

The role of nutrition in non‐alcoholic fatty liver disease: Pathophysiology and management

The role of nutrition in non‐alcoholic fatty liver disease: Pathophysiology and management

A Recent Research on Non Alcoholic Fatty Liver Disease

Lifestyle modifications for nonalcohol-related fatty liver disease: a network meta-analysis

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