Olive oil and body fat: a systematic review with<i>meta</i>-analysis

Santos, André Soares; Souza, Maria do Carmo; Machado, Adriane Moreira; Duarte, Camila Kümmel

doi:10.1039/d3fo00488k

Food Funct.

2023

DOI: 10.1039/d3fo00488k

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Olive oil and body fat: a systematic review withmeta-analysis

André Soares Santos

Maria do Carmo Souza

Adriane Moreira Machado³

et al.

Abstract: Diet composition has a great impact on body composition. Several studies have suggested a beneficial effect of adding olive oil to a calorie-restricted diet as a weight loss strategy. However,...

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2024

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Extract mixture of plants (OXYLIA) inhibits fat accumulation by blocking FAS-related factors and promoting lipolysis via cAMP-dependent PKA activation

Park,

Baek,

Lee

et al. 2024

Food & Nutrition Research

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Background: Obesity is characterized by an imbalance between energy intake and expenditure, leading to the excessive accumulation of triglycerides in adipose tissue. Objective: This study investigated the potential of Oxylia to prevent obesity in mice fed with a high-fat diet (HFD). Design: C57BL/6J mice were fed with one of the following five diets – AIN93G normal diet (normal control), 60% (HFD; control), HFD containing metformin at 40 mg/kg body weight (b.w.) (Met; positive control), HFD containing Oxylia at 30 mg/kg b.w. (O30), or HFD containing Oxylia at 60 mg/kg b.w. (O60) – for 15 weeks. Results: Mice under an HFD supplemented with Oxylia had decreased body weight gain, adipose tissue weight, and adipose tissue mass. In addition, triglyceride (TG), total cholesterol, and VLDL/LDL cholesterol levels were lower in the O60 groups than in the HFD-fed control group. Moreover, Oxylia supplementation decreased the expression of adipogenesis-related mRNAs and lipogenesis-related proteins while increasing the expression of lipolysis-related proteins in white adipose tissue and thermogenesis-related proteins in brown adipose tissue. Conclusions: These findings suggest that Oxylia has potential as a functional food ingredient for the prevention and treatment of obesity and related metabolic disorders.

show abstract

Extract mixture of plants (OXYLIA) inhibits fat accumulation by blocking FAS-related factors and promoting lipolysis via cAMP-dependent PKA activation

Park,

Baek,

Lee

et al. 2024

Food & Nutrition Research

View full text Add to dashboard Cite

show abstract

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Olive oil and body fat: a systematic review withmeta-analysis

Abstract: Diet composition has a great impact on body composition. Several studies have suggested a beneficial effect of adding olive oil to a calorie-restricted diet as a weight loss strategy. However,...

Cited by 1 publication

References 75 publications

Extract mixture of plants (OXYLIA) inhibits fat accumulation by blocking FAS-related factors and promoting lipolysis via cAMP-dependent PKA activation

Extract mixture of plants (OXYLIA) inhibits fat accumulation by blocking FAS-related factors and promoting lipolysis via cAMP-dependent PKA activation

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