Oliguric Renal Failure of Surgical Origin

Deciphering the mechanisms of the Na+/H+ exchanger-3 regulation in organ dysfunction

“…In IRI the decrease in urine output is associated with reduced GFR, but it may follow a paradoxical oliguric phase with increased salt excretion secondary to acute tubular necrosis (20,29,185). The natriuresis occurring as a result of IRI would involve a reduction in renal Na ϩ reabsorption along the nephron.…”

Estimations of Blood Volume During Course of Renal Failure

“…Despite vagotomy and gastrectomy he died from suture leakage and peritonitis on the 15th day. Gastro-intestinal haemorrhage of a degree to threaten survival has occurred in 7 of our 59 surgical patients, and is a considerable hazard in this group, as has been described by Shackman et al (1960). It has occurred in dialysed and non-dialysed patients, is often due to multiple gastric or duodenal ulcers, and has been treated conservatively except in the case described.…”

“…Physical signs, blood indices, and urine composition are all of value in distinguishing the two (Shackman et al, 1960). The estimation of blood volume will on occasion be of material assistance, and serial estimations aid in assessment of the efficiency of treatment.…”

The Scribner Arteriovenous Fistula for Haemodialysis

“…arteriovenous fistula for the treatmnent of patients with chronic renal failure and have been-able to maintain patency of the fistula for many months. The fistula may, however, be even more valuable for repeated haemodialysis in some cases of acute oliguric renal failure, particularly when there is rapid biochemical deterioration and haemodialysis is required every two or three days-f6r example, in cases of acute oliguric renal failure which complicates surgical or accidental trauma (Shackman et at., 1960). The fistula is particularly valuable wben extensive soft-tissue injury, burns, thrombophlebits after repeated venepuncture or intravenous infgsln, or skeletal injuries requiring extensive plaster-of-Paris casts limit access to swtable vins.…”