Oligosaccharide polyesters from roots of Polygala fallax

New Phenolics from Polygala fallax

“…(Polygalaceae) is a medicinal plant used as a tonic and antihepatitis drug in southern regions of the People's Republic of China . The occurrence of both triterpenoid saponins and oligosaccharide polyesters has been reported previously. In the course of our continuing investigation of bioactive natural products from folk medicinal plants used in the southern part of mainland China, we have investigated the phenolic constituents of P. fallax .…”

Naturally Occurring Cinnamic Acid Sugar Ester Derivatives

“…Of all the tetrasaccharide esters 255 – 279 (Figure 55, Figure 56, Figure 57, Figure 58, Figure 59 and Figure 60) [37,38,46,62,92,93,105,106,107], 23 are found in Polygalaceae plants Most of the phenylacrylic moieties are coumaroyl, feruloyl and sinapoyl groups. According to the core glycosyl type, these compounds can be classified into four groups, including the combination of fructose with three glucoses ( 255 – 274 , Figure 55, Figure 56 and Figure 57), rhamnose, fructose with two glucoses ( 277 – 278 , Figure 60), the other tetrasaccharide esters ( 275 , 276 , 279 , Figure 58, Figure 59 and Figure 60).…”

“…The structures of fallaxose A ( 277 ) and fallaxose B ( 278 ), found in the roots of Polygala fallax , are similar, except for the acetyl group and the glucose location. Both are esterified with ferulic acid [92].…”

“…To our knowledge, pentasaccharide esters 280 – 320 (Figure 61, Figure 62, Figure 63 and Figure 64) [11,12,46,92,93,107,108,109,110], hexsaccharide esters 321 – 333 (Figure 65, Figure 66, Figure 67, Figure 68, Figure 69, Figure 70 and Figure 71) [11,12,56,107,109,110], heptasaccharide esters 334 (Figure 72) [56] were all found in the Polygalaceae family and most of them form a series of similar type compounds. That is to say, CASEDs with higher carbon numbers are rarely found in plants outside the Polygalaceae .…”

Tetrasaccharide Multi-Esters and Xanthone Glycosides from the Roots of Polygala wattersii

“…We now report the isolation and structure elucidation of 10 new tetrasaccharide multi-esters, watteroses A−J ( 1 − 10 ), and two new xanthone glycosides, wattersiixanthones A ( 11 ) and B ( 12 ). Ten known oligosaccharide multi-esters isolated from this plant were identified by comparison of the spectral data with reported data, as reiniose G ( 13 ), fallaxose C ( 14 ), reiniose H ( 15 ), senegose F ( 16 ), senegose G ( 17 ), reiniose A ( 18 ), 6- O -benzoyl-3‘- O -3,4,5-trimethoxycinnamoyl-sucrose ( 19 ), 6- O -feruoyl-3‘-sinapoyl-sucrose ( 20 ), 3‘- O -feruloyl-6- O -sinapoyl-sucrose ( 21 ), 5 3‘,6-di- O -sinapoyl-sucrose ( 22 ), and a known xanthone glycoside identified as wubangziside B ( 23 ) . See Chart .…”