Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases

Mehta, Meenu; Deeksha,; Tewari, Devesh; Gupta, Gaurav; Awasthi, Rajendra; Singh, Harjeet; Pandey, Parijat; Chellappan, Dinesh Kumar; Wadhwa, Ridhima; Collet, Trudi; Hansbro, Philip M.; Kumar, Shobhit; Thangavelu, Lakshmi; Negi, Poonam; Dua, Kamal; Satija, Saurabh

doi:10.1016/j.cbi.2019.05.028

Cited by 306 publications

(116 citation statements)

References 104 publications

(111 reference statements)

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“…Dendrimers are another type of nanomaterial that have been explored for their potential application in the delivery of antigenic molecules in the management of influenza. Dendrimers are three-dimensional, branched and star-shaped delivery systems that possess unique properties such as great water solubility, good biocompatibility, and low polydispersity index [43] , [44] , [45] , [46] , [47] , [48] , [49] . Polypropyleneimine and polyaminoamine dendrimers are the most utilized for vaccine delivery against influenza virus, whereby a dose of dendrimer encapsulating various antigens has been found to elicit powerful antibody and T-cell responses against influenza H1N1 virus [44] .…”

Section: Evaluation Of the Hypothesismentioning

confidence: 99%

Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis

Chan

Mehta

et al. 2020

Medical Hypotheses

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Outbreaks of influenza infections in the past have severely impacted global health and socioeconomic growth. Antivirals and vaccines are remarkable medical innovations that have been successful in reducing the rates of morbidity and mortality from this disease. However, the relentless emergence of drug resistance has led to a worrisome increase in the trend of influenza outbreaks, characterized by worsened clinical outcomes as well as increased economic burden. This has prompted the need for breakthrough innovations that can effectively manage influenza outbreaks. This article provides an insight into a novel hypothesis that describes how the integration of nanomedicine, with the development of drugs and vaccines can potentially enhance body immune response and the efficacies of anti-viral therapeutics to combat influenza infections.

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Section: Evaluation Of the Hypothesismentioning

confidence: 99%

Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis

Chan

Mehta

et al. 2020

Medical Hypotheses

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“…The targeted therapy provides better treatment with minimal side effects compared to other treatments for cancer. It is noted for 3 main outcomes, namely, locoregional tumor control without affecting other organs, disease-free survival by cancer cell eradication, to its core, and quality of life by providing a cure in such a way that the disease does not occur in an individual (Mehta, 2019).…”

Section: Outcomes Of Targeted Therapy In Oral Cancermentioning

confidence: 99%

A Concise Review on Targeted Therapy for Oral Cancer

Thariny

Ezhilarasan

Brundha

2020

ijrps

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Oral Cancer has become a center of attraction in the world, causing health problems. Carcinoma that involves the lip, tongue, mouth surface, palate, and throat is also serious if not diagnosed and treated. Current treatment strategies involve surgical removal, using chemotherapeutic drugs and radiation therapy. The event of targeted therapy aid in medicine together with oral cancers is that the basic dependence of neoplasm cells on biological pathways which might be coupled to medicine that inhibit those pathways. The resistance of tumor cells to anticancer drugs is a known method which is investigated experimentally at the molecular level. Immunotherapeutic agent resistance is thought to affect the efficacy of anticancer remedies. The induced or intrinsic drug resistance has a strong effect on the survival and cancer growth prognosis by suppression of cancer-associated cell signaling pathways of cancer patients. Targeted therapy also has a significant inhibitory ability, thus demonstrating the high quality of treatment. Hence this concise review discusses the implementation of molecular targeted therapy in the treatment of oral cancer.

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“…The advantages of Intraoral cameras are early identi ication of oral medical issues, improved patient-doctors connection, improves the quality of the treatment, for future case documentation, upgrades doctors believability and better protection claims (Neuman, 1996). The fundamental objective in the utilization of intraoral cameras is to survey and analyze oral medical issues (Mehta et al, 2019). The photos and videos taken by the intraoral camera will serve as a basis of the oral health condition of the patients.…”

Section: Intraoral Cameramentioning

confidence: 99%

Use of digital dentistry in clinical practice among dental practitioners - A review

Surya

Lakshmi

Devi

2020

ijrps

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The aim of the study is to find an opinion about the use of digital dentistry in clinical practice among dental practitioners. Digital dentistry is the use of dental technologies and devices that incorporate digital (or) computer controlled components that carry out dental procedures than using mechanical (or) electrical tools. A detailed study is done by reviewing several articles about digital dentistry in dental practice. Many dentists are focusing on advanced dentistry now-a-days, which causes them to take care of conventional issues with present day arrangements. The purpose behind this article is to analyze the idea of computerized dentistry, its focal points and restrictions, and offer expressions and perceptions on explicit areas of advanced dentistry dependent on research, understanding, and correspondence with clinicians around the world. It is expected to give a functional perspective on computerized dentistry, an improvement for more prominent selection of the areas that are concerned with digital dentistry, and quicker incorporation of new innovations.

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Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases

Cited by 306 publications

References 104 publications

Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis

Advanced drug delivery systems can assist in managing influenza virus infection: A hypothesis

A Concise Review on Targeted Therapy for Oral Cancer

Use of digital dentistry in clinical practice among dental practitioners - A review

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