Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta‐analysis

Rabie, Nader; Magann, Everett F.; Steelman, Susan; Ounpraseuth, S.

doi:10.1002/uog.15929

Cited by 107 publications

(90 citation statements)

References 40 publications

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“…The mean birth weight was lower in women with oligohydramnios by 162 g and the incidences of low birth weight and preterm birth were higher. Similar results have been found in studies from high-income settings [4,8,9,[11][12][13]. During the parent study we emphasized appropriate referral and hospital care for conditions diagnosed by ultrasound including oligohydramnios.…”

Section: Discussionsupporting

confidence: 79%

“…The overall prevalence of oligohydramnios on a third trimester ultrasound examination performed on average around 35 weeks of pregnancy was 0.7% across sites, with the lowest incidence in Zambia and the DRC (0.2%) and highest in Pakistan (1.5%). These rates are within the ranges found in high-income countries and provide evidence regarding the rate of oligohydramnios in LMIC settings [4,[8][9][10][11][12].…”

Section: Discussionsupporting

confidence: 57%

“…Fetal health can be seriously compromised by oligohydramnios, with complications such as pulmonary hypoplasia, meconium aspiration syndrome, fetal compression and, in cases of prolonged rupture of membranes, infections [1,2,8,9]. Women with oligohydramnios are more likely to have an infant with low birth weight [10][11][12][13]. In terms of burden of care, higher rates of cesarean delivery for fetal distress and neonatal admission to the intensive care unit have also been associated with oligohydramnios [4,8].…”

Section: Introductionmentioning

confidence: 99%

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Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries

et al. 2020

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Background: Oligohydramnios is a condition of abnormally low amniotic fluid volume that has been associated with poor pregnancy outcomes. To date, the prevalence of this condition and its outcomes has not been well described in low and low-middle income countries (LMIC) where ultrasound use to diagnose this condition in pregnancy is limited. As part of a prospective trial of ultrasound at antenatal care in LMICs, we sought to evaluate the incidence of and the adverse maternal, fetal and neonatal outcomes associated with oligohydramnios. Methods: We included data in this report from all pregnant women in community settings in Guatemala, Pakistan, Zambia and the Democratic Republic of Congo (DRC) who received a third trimester ultrasound as part of the First Look Study, a randomized trial to assess the value of ultrasound at antenatal care. Using these data, we conducted a planned secondary analysis to compare pregnancy outcomes of women with to those without oligohydramnios. Oligohydramnios was defined as measurement of an Amniotic Fluid Index less than 5 cm in at least one ultrasound in the third trimester. The outcomes assessed included maternal morbidity and fetal and neonatal mortality, preterm birth and low-birthweight. We used pairwise site comparisons with Tukey-Kramer adjustment and multivariable logistic models using general estimating equations to account for the correlation of outcomes within cluster.Results: Of 12,940 women enrolled in the clusters in Guatemala, Pakistan, Zambia and the DRC in the First Look Study who had a third trimester ultrasound examination, 87 women were diagnosed with oligohydramnios, equivalent to 0.7% of those studied. Prevalence of detected oligohydramnios varied among study sites; from the lowest of 0.2% in Zambia and the DRC to the highest of 1.5% in Pakistan. Women diagnosed with oligohydramnios had higher rates of hemorrhage, fetal malposition, and cesarean delivery than women without oligohydramnios. We also found unfavorable fetal and neonatal outcomes associated with oligohydramnios including stillbirths (OR 5.16, 95%CI 2.07, 12.85), neonatal deaths < 28 days (OR 3.18, 95% CI 1.18, 8.57), low birth weight (OR 2.10, 95% CI 1.44, 3.07) and preterm births (OR 2.73, 95%CI 1.76, 4.23). The mean birth weight was 162 g less (95% CI -288.6, − 35.9) with oligohydramnios. Conclusions:Oligohydramnos was associated with worse neonatal, fetal and maternal outcomes in LMIC. Further research is needed to assess effective interventions to diagnose and ultimately to reduce poor outcomes in these settings.Trial registration: NCT01990625.

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Section: Discussionsupporting

confidence: 79%

Section: Discussionsupporting

confidence: 57%

Section: Introductionmentioning

confidence: 99%

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Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries

et al. 2020

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“…Oligohydramnios also increases maternal risk interms of labor induction and cesarean section and their attendant risks [11,28]. Studies done among different study groups in United States, Nigeria, Nepal, India and Pakistan show cesarean section rates of 20.2%, 30.8%, 64% and 83.6% respectively [8,9,29,30].…”

Section: Maternal Outcomementioning

confidence: 99%

Determinants of Maternal and Neonatal Outcomes of Oligohydramnios After 37+0 Weeks of Gestation in Mekelle Public Hospitals, Northern Ethiopia

Gidey

Gebreezgabher

Yemane

et al. 2020

Preprint

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Background Oligohydramnios is a state of deficient amniotic fluid defined objectively using ultrasound measurements as single deepest vertical pocket less than 2 centimeters and/or amniotic fluid index less than 5 centimeters. It has been correlated with conditions that threaten both maternal and fetal health. The aim of this stuy is to assess determinants of adverse maternal and perinatal outcome in women with oligohydramnios after 37+0 weeks in Ayder Comprehensive Specialized Hospital and Mekelle General Hospital from April 1, 2018 – March 31, 2019.Methods This was prospective observational study. Total population purposive sampling method was employed to collect data prospectively. Result During the study period, there were a total of 10,451 deliveries, of which 273 were complicated with oligohydramnios, making the prevalence of term oligohydramnios 2.6%. The composite adverse perinatal and maternal outcomes were 38.1% and 89.4% respectively. Primigravidity, degree of oligohydramnios, presence of intrauterine growth restriction and postterm pregnancy were associated with adverse perinatal outcome. Degree of oligohydramnios and hypertensive disorders of pregnancy were found to be predictor of composite adverse maternal outcome. Conclusion Appreciation of determinants of composite adverse maternal and neonatal outcome can aid prompt interventions and mobilization of resources for resuscitation and early transfer to neonatal intensive care unit. Knowledge of determinants of maternal outcome can serve as a tool for patient counseling and for anticipation of maternal complications.

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“…Oligohydramnios can be defined in many ways: Amniotic fluid volume less than 5% for a specific gestational age, AFI< 5cm or maximal deepest pocket<2 cm. 1 Infact, the term oligohydramnios, defined as Amniotic Fluid Index ≤5 was originally defined by Phelan et al, The ultrasonographic diagnosis of oligohydramnios is usually based on AFV≤5 cm or a single deepest pocket (SDP) of amniotic fluid ≤2 cm. 2,3 Of these , SDP is the best method for diagnosing it 4; most studies evaluate adverse outcomes using AFI.…”

Section: Introductionmentioning

confidence: 99%

Neonatal and maternal outcome in term primigravida with isolated oligohydramnios

Agarwal¹,

Gupta²

2018

Int J Reprod Contracept Obstet Gynecol

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Background: The aim of this study is to evaluate the maternal and perinatal outcome in term primigravida with isolated oligohydramnios.Methods: A retrospective, case–control study was carried out in the department of OBG, School of Medical Sciences and Research, Sharda Hospital, Greater Noida from November 2014 to October 2017. The study population comprised of low-risk primigravida with singleton, term pregnancy, with vertex presentation and intact membranes. After meeting the inclusion and exclusion criterion, the study population was divided into cases (n = 51) and control group (176) and the results were analyzed in reference to rate of induction of labour, C. Section rate and the perinatal outcome.Results: Isolated oligohydramnios is associated with increased rate of induction of labour and increased operative interference, but perinatal outcome in terms of mean birth weight, Apgar score at 5 min and NICU admissions for over 24 hours, are not statistically significant in comparison with control group.Conclusions: Isolated oligohydramnios is not an indicator of adverse perinatal outcome.

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Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta‐analysis

Cited by 107 publications

References 40 publications

Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries

Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries

Determinants of Maternal and Neonatal Outcomes of Oligohydramnios After 37+0 Weeks of Gestation in Mekelle Public Hospitals, Northern Ethiopia

Neonatal and maternal outcome in term primigravida with isolated oligohydramnios

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