Olfactory Ecto-Mesenchymal Stem Cells in Modeling and Treating Alzheimer’s Disease
Hongmin Wang,
Abena Dwamena
Abstract:Alzheimer’s disease (AD) is a condition in the brain that is marked by a gradual and ongoing reduction in memory, thought, and the ability to perform simple tasks. AD has a poor prognosis but no cure yet. Therefore, the need for novel models to study its pathogenesis and therapeutic strategies is evident, as the brain poorly recovers after injury and neurodegenerative diseases and can neither replace dead neurons nor reinnervate target structures. Recently, mesenchymal stem cells (MSCs), particularly those fro… Show more
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