“…Behavioral analyses of these mice showed several phenotypes, such as a PPI deficit that is reversible by haloperidol treatment, increased compulsive behaviors, impaired locomotor coordination, increased sensitivity to phencyclidine, and impaired odorant discrimination. These behavioral phenotypes are regarded as rodent correlates to symptoms of schizophrenia (Bottas et al, 2005;Braff and Geyer, 1990;Murray, 2002;Nguyen et al, 2010). However, many clinical features of schizophrenia can also be observed in other psychiatric disorders like bipolar disorder (Taylor et al, 1993;Tsuang et al, 1980;Valles et al, 2000) and genetic risk factors contributing to psychiatric disorders, including G72/G30 that are typically associated with more than one disorder.…”