Olfactory Disturbance Caused by Chronic Sinusitis

Abstract

Sinusitis has been reported to be one of the major causative etiologies of olfactory disorder. According to our data during last 3 years, 47.5% of all cases of olfactory disorder were attributed to sinusitis. Persistent olfactory disturbance was often critical even after resection of the patho

Olfactory dysfunction and the role of stem cells in the regeneration of olfactory neurons

“…Examining inflammatory damage in a sinusitis model, Egawa et al compared the extent of damage to the olfactory epithelium and respiratory epithelium. Their findings suggest that olfactory epithelial inflammation stands as another critical pathogenic factor impeding the recovery of olfactory sensitivity [ 34 ]. Additionally, research indicates a clear interplay between nasal microbiota imbalance, differential metabolites, and elevated inflammatory mediators in patients with olfactory dysfunction [ 32 ].…”