Olfactory Disruption

Olfactory receptors in Bactrocera species for sustainable fruit fly management: A review and future perspectives

“…They can be classified as stimulants, repellents, attractants, arrestants or deterrents (Jang & Light, 1996), which contribute to the following: behavioural roles, sex attractants, species recognition, cast recognition, aggregation, dispersal behaviour, alarm recruitment, cues or some other odour within colony (Yang et al, 2021). Since semiochemicals can determine a particular situation of insects (e.g., oviposition site, mating and feeding), they can be used for selective pest control via biological control, mating disruption and feeding deterrence though the dynamic strategy attract, trap and kill the target pest (Norin, 2007; Smagghe et al, 2019; Sparks et al, 2015).…”

Volatile pyrethroid spatial repellents for malaria prevention

“…Most spatial repellents that are commercially available or in development use volatile pyrethroids as their active ingredients, which are known not only to cause true repellency but also cause additional modes of action, including feeding inhibition, insecticidal activity and disarming (Tambwe 2022), depending on the dose used (Bibbs 2017). Feeding inhibition is defined as the inability of adult female mosquitoes to complete the sequence of behaviours that result in a blood meal, due to inhibition or excitation of olfactory receptor neurons (Sparks 2015), consequently reducing human-vector contact. Insecticidal activity or toxicity results in death of mosquitoes before biting (pre-prandial mortality) or a er biting (post-prandial mortality), protecting both users and non-users within a community (Denz 2021; ten Bosch 2019).…”

Editorial: Improving Neuropharmacology using Big Data, Machine Learning and Computational Algorithms

“…The majority of diseases transmitted by mosquito including malaria, dengue, West Nile virus, encephalitis and Zika fever have complications that affect the neurological systems [ 37 - 39 ]. Understanding the molecular role of the vector proteins is critical to developing repellents, vector controlling agents and other chemical agents to control mosquitoes that spread viral diseases [ 40 , 41 ]. In their research paper, Rithvik and Sowdhamini present results from a challenging task of modeling an ion channel from Anopheles gambiae .…”