Olfactory cleft opacity and CT score are predictive factors of smell recovery after surgery in nasal polyposis

Vandenhende‐Szymanski, Claire; Hochet, Baptiste; Chevalier, Dominique; Mortuaire, G.

doi:10.4193/rhin14.160

Cited by 37 publications

(42 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two studies did not find any association between age and olfactory dysfunction . Within CRS‐specific factors, a higher Lund‐Mackay (LM) computed tomography (CT) score was most frequently associated with poorer smell with 11 studies reporting this relationship . Remaining studies did not examine this association.…”

Section: Resultsmentioning

confidence: 98%

“…One study of 30 CRSwNP patients reported the prevalence of normosmia, hyposmia, and anosmia as 6.7%, 30.0%, and 63.3%, respectively, using the European Test of Olfactory Capabilities (Table ).…”

Section: Resultsmentioning

confidence: 99%

“…57,64 Within CRS-specific factors, a higher Lund-Mackay (LM) computed tomography (CT) score was most frequently associated with poorer smell with 11 studies reporting this relationship. 18,21,27,38,40,50,51,53,57,61,64 Remaining studies did not examine this association. Among comorbid factors impacting smell, nasal polyposis was most frequently associated with olfactory dysfunction, with 10 studies reporting an association.…”

Section: Factors Associated With Olfactory Dysfunctionmentioning

confidence: 99%

See 2 more Smart Citations

The prevalence of olfactory dysfunction in chronic rhinosinusitis

et al. 2016

View full text Add to dashboard Cite

Objective Many studies have reported that olfactory dysfunction frequently occurs in chronic rhinosinusitis (CRS) populations; however, the prevalence and degree of olfactory loss has not been systematically studied. The aims of this study are to use combined data to report the prevalence of olfactory dysfunction and to calculate weighted averages of olfactory test scores in CRS patients. Data Sources A search was conducted in PubMed and Scopus, following the methods of Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. Review Methods Studies reporting the prevalence of olfactory dysfunction using objective measures or olfactory test scores using validated scales were included. Results A total of 47 articles were included in systematic review and 35 in the pooled data analysis. The prevalence of olfactory dysfunction in chronic rhinosinusitis was found to be 30.0% using the Brief Smell Identification Test, 67.0% using the 40-item Smell Identification Test, and 78.2% using the total Sniffin’ Sticks score. Weighted averages ± standard deviation of olfactory test scores were 25.96±7.11 using the 40-item Smell Identification Test, 8.60±2.81 using the Brief Smell Identification Test, 21.96±8.88 using total Sniffin’ sticks score, 5.65±1.51 using Sniffin’ Sticks threshold, 9.21±4.63 using Sniffin’ Sticks discrimination, 9.47±3.92 using Sniffin’ Sticks Identification, and 8.90±5.14 using the questionnaire for olfactory disorders-negative statements. Conclusion In chronic rhinosinusitis populations, a significant percentage of patients experience olfactory dysfunction and mean olfactory scores are within the dysosmic range.

show abstract

Section: Resultsmentioning

confidence: 98%

Section: Resultsmentioning

confidence: 99%

Section: Factors Associated With Olfactory Dysfunctionmentioning

confidence: 99%

See 1 more Smart Citation

The prevalence of olfactory dysfunction in chronic rhinosinusitis

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Our hypothesis is that the current OCES system will more closely predict olfaction than a more generalized instrument that ignores the olfactory cleft. Studies examining CT scans have shown that opacification of the olfactory cleft is more predictive of olfaction than sinus‐specific opacification, at least with respect to patients with polyps . If similar findings are true with endoscopy, then the OCES might be an informative measure to include in future studies that aim to either predict olfaction in patients with CRS or explore mechanisms of olfactory loss.…”

Section: Discussionmentioning

confidence: 96%

The Olfactory Cleft Endoscopy Scale correlates with olfactory metrics in patients with chronic rhinosinusitis

Soler

Hyer

Karnezis

et al. 2015

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

Introduction Olfactory loss affects a majority of patients with chronic rhinosinusitis (CRS). Traditional objective measures of disease severity, including endoscopy scales, focus upon the paranasal sinuses and often have weak correlation to olfaction. Methods Adults with CRS were prospectively evaluated by blinded reviewers with a novel Olfactory Cleft Endoscopy Scale (OCES) that evaluated discharge, polyps, edema, crusting and scarring of the olfactory cleft. Objective olfactory function was assessed using “Sniffin’ Sticks testing, including composite threshold-discrimination-identification (TDI) scores. Olfactory-specific quality-of-life was evaluated using the short modified version of the Questionnaire of Olfactory Disorders (QOD-NS). Inter- and intra-rater reliability was assessed among 3 reviewers for OCES grading. Multivariate linear regression was then used to test associations between OCES scores and measures of olfaction, controlling for potential confounding factors. Results The OCES score was evaluated in 38 patients and had a high overall reliability (ICC=0.92; 95% CI: 0.91–0.96). The OCES significantly correlated with objective olfaction as measured by TDI score (p<0.001), with TDI score falling by 1.13 points for every 1 point increase in OCES score. Similar significant associations were found for threshold, discrimination, and identification scores (p<0.003 for all) after controlling for age, gender, race, and reviewer/review. The OCES was also highly associated with patient-reported QOD-NS scores (p=0.009). Conclusion A novel olfactory cleft endoscopy scale shows high reliability and correlates with both objective and patient-reported olfaction in patients with CRS. Further studies to determine prognostic value and responsiveness to change are warranted.

show abstract

“…L‐M CT scores have been shown to predict the severity of symptoms for nasal obstruction, and sleep disturbance, but not other common symptoms of CRS . Other studies suggest that preoperative sinus CT scans are correlated with olfactory loss and can predict postoperative smell recovery . Patients with more severe L‐M CT scores typically have better surgical outcomes and are more likely to undergo surgery .…”

Section: Discussionmentioning

confidence: 99%

Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis

Falco

Thomas

Quin

et al. 2016

Int Forum Allergy Rhinol

View full text Add to dashboard Cite

show abstract

Olfactory cleft opacity and CT score are predictive factors of smell recovery after surgery in nasal polyposis

Abstract: With a convenient psychophysical test, we showed that olfactory cleft opacification and CT scan score could be predictive factors of olfaction disorder severity and improvement after ESS in CRSwNP. These results need to be strengthened in the long term with a larger panel of patients.

Cited by 37 publications

References 17 publications

The prevalence of olfactory dysfunction in chronic rhinosinusitis

The prevalence of olfactory dysfunction in chronic rhinosinusitis

The Olfactory Cleft Endoscopy Scale correlates with olfactory metrics in patients with chronic rhinosinusitis

Lack of correlation between patient reported location and severity of facial pain and radiographic burden of disease in chronic rhinosinusitis

Contact Info

Product

Resources

About