Oleuropein mediated autophagy begets antimalarial drug resistance
Prakriti Sharma,
Neil Roy Chaudhary,
Sonia Devi
et al.
Abstract:Drug resistance in Plasmodium falciparum presents a formidable challenge to the humanity. And, unavailability of an effective vaccine worsens the situation further. Autophagy is one of the mechanisms employed by parasite to evade drug pressure to survive. Autophagy induced by the P. falciparum in response to the oleuropein pressure may answer many questions related to the parasite survival as well as evolving drug tolerance. The survival/autophagy axis could be an important avenue to explore in order to addres… Show more
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