Abstract:Mania possibly induced by clozapine: a case report Manic shift can be caused by the use of atypical antipsychotics. Hypomanic/manic episodes caused by olanzapine, risperidone, quetiapine, ziprasidone, amisulpride, aripiprazole, zotepine, perospirone, and paliperidone have been frequently described in the literature. The proposed causes of mania/hypomania switching are due to blockages of 5HT2A and D2 receptors, enhancement of 5HT1A receptors, and dopamine release in the prefrontal/frontal regions. There have b… Show more
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