Office-based Core Needle Biopsy of Bone and Soft Tissue Malignancies: An Accurate Alternative to Open Biopsy with Infrequent Complications

Abstract

Level II, diagnostic study. See the Guidelines for Authors for a complete description of the level of evidence.

Current Concepts in the Biopsy of Musculoskeletal Tumors

“…However, there was not a statistically significant difference ( > 0.05). These findings correlate well with the recent literature, indicating no difference in accuracy between core and open biopsy [5,16].…”

“…In fact, the staging of the lesion helps determine the exact anatomic approach to the tumor and specifies the region of the tumor that represents the underlying disease [2]. As an alternative to open biopsy, percutaneous core-needle biopsy techniques have been developed [5].…”

Computed Tomography-Guided Core Needle Biopsy versus Incisional Biopsy in Diagnosing Musculoskeletal Lesions

“…10 In addition, we tried not to biopsy lesions that appeared to be low-grade lipomatous tumours, low-grade cartilaginous tumours, or myxoid, as they are difficult to interpret histologically. 3 Table 4 Accuracy of computed tomography-guided core needle biopsy (CT-guided CNB) and incisional biopsy for bone versus softtissue lesions Table 5 Accuracy of computed tomography-guided core needle biopsy (CT-guided CNB) and incisional biopsy in terms of lesion type lipomatous tumour, well-differentiated liposarcoma, or low-grade chondrosarcoma can be safely treated by marginal resection without biopsy 17,18 or extended intralesional curettage, 19,20 as the risk of recurrence is low. Nonetheless, in indeterminate lesions, biopsy is still recommended.…”

Soft Tissue Sarcomas

“…Core-needle biopsies have reported accuracy rates in the literature of 80-91 %, which in all studies is moderately inferior to an open incisional biopsy (94-100 %). However, core-needle biopsy is safe, minimally invasive, and cost effective [24][25][26][27].…”