Of ethnicity, environment, and microbiota

Jayaraman, Sundararajan

doi:10.1038/s41423-018-0179-8

Cited by 5 publications

(1 citation statement)

References 15 publications

(14 reference statements)

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“…The use of drugs can impact the gut microbiota and, in turn, the gut microbiota can influence drug metabolism [41][42][43]. Ethnicity and place of residence have also been identified as influencing factors [44][45][46][47][48][49][50][51]. In addition, other factors such as stress, tobacco smoking and sleep disorders play a role in shaping the gut microbiota [52][53][54][55][56][57][58][59][60][61][62] (Figure 1).…”

Section: The Roles Of the Gut Microbiotamentioning

confidence: 99%

Modulation of the Gut Microbiota by Nutrition and Its Relationship to Epigenetics

Ferenc,

Sokal-Dembowska,

Helma

et al. 2024

IJMS

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The intestinal microbiota is a community of microorganisms inhabiting the human intestines, potentially influencing both physiological and pathophysiological processes in the human body. Existing evidence suggests that nutrients can influence the modulation of the gut microbiota. However, there is still limited evidence regarding the effects of vitamin and mineral supplementation on the human gut microbiota through epigenetic modification. It is plausible that maintaining an adequate dietary intake of vitamin D, iron, fibre, zinc and magnesium may have a beneficial effect on alleviating inflammation in the body, reducing oxidative stress, and improving the condition of the intestinal microbiota through various epigenetic mechanisms. Moreover, epigenetics involves alterations in the phenotype of a cell without changing its fundamental DNA sequence. It appears that the modulation of the microbiota by various nutrients may lead to epigenetic regulation. The correlations between microbiota and epigenetics are potentially interdependent. Therefore, the primary objective of this review is to identify the complex relationships between diet, gut microbiota, and epigenetic regulation. These interactions could play a crucial role in systemic health.

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