Oesophageal cancer: an overview of a deadly disease

Re, White; Parker, Robert K.

doi:10.4314/aas.v1i1.45794

Cited by 2 publications

(2 citation statements)

References 61 publications

(81 reference statements)

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“…This is similar to a recent study done locally by Ojuka et al which had a mean age of 57.7 years at diagnosis (7). Earlier studies by Patel et al in 2013, White in 2007 and Wakhisi et al in 2002 had similar findings (8,9,10). The male to female ratio for this study was 1.7:1.…”

Section: Discussionsupporting

confidence: 60%

CT Pre-Operative Imaging of the Esophagus: Is Inclusion of Abdomen Necessary?

Kamanda¹

2020

Ann Afr Surg.

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Background: Esophageal carcinoma is the third commonest tumor in Kenya with one of the highest mortality rates. Locally, the 2019 Kenya National Cancer Treatment Protocols recommend CT chest and abdomen as the basic imaging tool. The aim of this study was to determine the necessity of including the abdomen while scanning patients with cancer of the esophagus. Methods: Fifty consecutive patients with esophageal cancer who underwent CT imaging were included. Results: 32 male patients (64%) and 18 (36%) female patients. 4 patients (8%) had a CT diagnosis of upper third cancer of the esophagus; 20 patients (40%) had middle third cancer; and 26 patients (52%) had lower third cancer. Patients with middle and lower third esophagus tumors had nodal and distant metastases to the upper abdomen. Conclusion: Preoperative CT with the inclusion of abdomen is essential for patients with middle and lower third tumors. None of the patients with upper third tumors had metastases to the abdomen. Further studies with a larger sample size are needed to assess the necessity of including abdomen in CT scan in these patients. Keywords: Esophageal cancer, CT scan, Abdomen, Diagnostic yield

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Section: Discussionsupporting

confidence: 60%

CT Pre-Operative Imaging of the Esophagus: Is Inclusion of Abdomen Necessary?

Kamanda¹

2020

Ann Afr Surg.

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“…Since 1966, western Kenya has been thought to be a high‐risk region for EC, 7 despite less study than other endemic areas. Because of the inadequacy of reliable cancer or death registries, it is impossible to report an accurate incidence of EC or any other malignancy within Kenya 8 . The Nairobi Cancer Registry recently reported all pathology‐confirmed cases of cancer registered in the Nairobi area during 2000–2002.…”

Section: Introductionmentioning

confidence: 99%

Frequent occurrence of esophageal cancer in young people in western Kenya

Parker

Dawsey

Abnet

et al. 2010

Diseases of the Esophagus

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Esophageal cancer has a strikingly uneven geographical distribution, resulting in focal endemic areas in several countries. One such endemic area is in western Kenya. We conducted a retrospective review of all pathology-confirmed malignancies diagnosed at Tenwek Hospital, Bomet District, between January 1999 and September 2007. Tumor site, histology, sex, age, ethnicity, and location of residence were recorded. Cases were analyzed within and outside a traditional catchment area defined as ≤ 50 km from the hospital. Since 1999, the five most common cancer sites were esophagus, stomach, prostate, colorectum, and cervix. Esophageal cancer accounted for 914 (34.6%) of the 2643 newly diagnosed cancers, and showed increasing trends within and outside the catchment area. Fifty-eight (6.3%) patients were ≤ 30 years old and 9 (1%) were ≤ 20 years old; the youngest patient was 14 at diagnosis. Young cases (≤30) were more common among patients of Kalenjin ethnicity (9.2%) than among other ethnicities (1.7%) (odds ratio (95%CI) 5.7 (2.1–15.1)). This area of western Kenya is a high-risk region for esophageal cancer, and appears unique in its large proportion of young patients. Our findings support the need for further study of both environmental and genetic risk factors for esophageal cancer in this area.

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Oesophageal cancer: an overview of a deadly disease

Cited by 2 publications

References 61 publications

CT Pre-Operative Imaging of the Esophagus: Is Inclusion of Abdomen Necessary?

CT Pre-Operative Imaging of the Esophagus: Is Inclusion of Abdomen Necessary?

Frequent occurrence of esophageal cancer in young people in western Kenya

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