Odontogenic Myxoma with Diffuse Calcifications: A Case Report and Review of the Literature

Lahey, Edward T.; Woo, Sook‐Bin; Park, Heekyung

doi:10.1007/s12105-012-0387-y

Cited by 28 publications

(31 citation statements)

References 17 publications

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“…O mixoma odontogênico representou o terceiro tumor odontogênico mais frequente com 7.03%, depois do amelobastoma, e odontoma (9) . Alguns trabalhos trazem ainda, achados histológicos incomuns, como a presença de corpos calcificados de composição cemento-óssea e ilhas de epitélio odontogênico ativo (4,(10)(11) .…”

Section: Abstract: Myxoma Odontogenic Tumors Retrospective Studiesunclassified

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Estudo retrospectivo de casos de mixoma odontogênico diagnosticados em um Serviço de Histopatologia Oral / Retrospective study of odontogenic myxoma cases diagnosed in an Oral Pathology Center

Carvalho

Pérez

Castro

et al. 2019

Arq Med Hosp Fac Cienc Med Santa Casa São Paulo

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Declaração isenção e de conflito de interesse: Os autores declaram não haver conflito de interesse e nenhum apoio financeiro. A presente pesquisa está em conformidade com as leis atuais do Brasil, em matéria de normas éticas. Resumo Objetivo: Estabelecer o perfil demográfico, clínico e imagenológico dos casos de mixoma odontogênico (MO). Métodos: Foi realizado um estudo do tipo retrospectivo, a partir do acervo do laboratório de histopatologia oral da Universidade Federal de Pernambuco no qual foram revisados todos os casos de mixoma odontogênico diagnosticados no período de período de 2000 a 2018, segundo os dados obtidos da ficha clínica de solicitação de exame histológico, com posterior reavaliação microscópica. A análise estatística foi de caráter descritivo. Resultados: Foram encontrados 10 casos de mixoma odontogênico, o que representou 0.15% de todas as lesões diagnosticadas no período. O mixoma acometeu principalmente mulheres na terceira década de vida. A localização mais comum foi a mandíbula, e a principal característica foi o aumento de volume assintomático. Radiograficamente as lesões eram radiolúcidas e multiloculares. Em todas as lesões foram observadas as típicas células de origem mesenquimal, fusiformes, arredondadas ou estreladas, dispersas em uma matriz mixoide abundante. Tempo de evolução médio de 22 meses. Conclusão: O MO acometeu principalmente mulheres na terceira década de vida. As lesões em sua maioria ocorreram em mandíbula, assintomáticas, sendo o aumento de volume o sinal clínico mais frequente. Não foram encontrados achados histológicos incomuns. Abstract Objective: To establish the demographic, clinical and imaging profile of patients diagnosed with odontogenic myxoma (OM). Methods: this retrospective study was carried out from the collection of the laboratory of oral pathology of the Federal University of Pernambuco, in which all cases of odontogenic myxoma diagnosed during the period from 2000 to 2018 were reviewed, according to data obtained from the record histological examination request. Subsequently, all OM cases were reassessed microscopically. A descriptive statistical analysis was performed. Results: There were found ten cases of odontogenic myxoma, representing 0.15% of all lesions diagnosed in the period. The myxoma mainly affected women in the third decade of life. The most common location was the mandible, and the main characteristic was the asymptomatic volume increase. Radiographically the lesions were radiolucent and multilocular. In all of the lesions, typical mesenchymal, fusiform, rounded or stellate cells dispersed in an abundant myxoid matrix were observed. Conclusions: OM had preference for women in the third decade of life. The lesions occurred mostly in the mandible, asymptomatic, being the volume increase the most frequent clinical sign. There was no unusual histological findings.

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Section: Abstract: Myxoma Odontogenic Tumors Retrospective Studiesunclassified

“…Assim como na maior parte da literatura (1,2,4,11,13,16,18) , nesta amostra houve maior número de casos na mandíbula. Antagonicamente, dois estudos multicêntricos realizados no Brasil mostraram predileção pela maxila.…”

Section: Casounclassified

Estudo retrospectivo de casos de mixoma odontogênico diagnosticados em um Serviço de Histopatologia Oral / Retrospective study of odontogenic myxoma cases diagnosed in an Oral Pathology Center

Carvalho

Pérez

Castro

et al. 2019

Arq Med Hosp Fac Cienc Med Santa Casa São Paulo

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“…Rates of recurrences have an average of approximately 25% and may be explained mainly by its gelatinous aspect and the fact it does not have a capsule . The overall prognosis is good, and metastasis does not occur …”

Section: Introductionmentioning

confidence: 99%

Odontogenic myxoma: A 63‐year retrospective multicenter study of 85 cases in a Brazil population and a review of 999 cases from literature

Vasconcelos

Silveira

Gomes

et al. 2017

J Oral Pathology Medicine

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Background Odontogenic myxoma (OM) is an uncommon neoplasm of the jaws. Considering the importance of defining the relative incidence and demographic profile of these lesions in South America, the aim of this study was to analyze the clinical and imagiological features of OM from three South American oral pathology services and to discuss these findings in light of the literature. Methods Data regarding age, gender, anatomic site, and imagiological features from 85 cases of OM were collected. Additionally, we did a review of OM studies published in three electronic databases. Results Among 63 450 oral biopsies, 1178 (1.85%) were odontogenic tumors (World Health Organization ‐ 2017), of which 85 (7.21%) met the criteria of OM. The mean age was 30.7 years (range: 10‐61 years; SD: 12.22). Forty‐five (52.9%) cases occurred in females and 40 (47.1%) in males (ratio: 1:1.12). Maxilla was affected in 44 cases (53%) and mandible in 39 (47%). Of the 41 informed cases (48.2%), all of them were radiolucent lesions. The literature review indicated a majority of mean ages in third decade and a predilection for females, mandible, and multilocular radiolucent lesions. Conclusions The features of OM samples have strong similarity to that reported in studies from other continents. It is possible to infer that geographic variation does not help to explain some differences observed in the clinical features of OM.

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“…It is a locally aggressive lesion which infiltrates adjacent structures and may recur [3][4][5]. It may reach a significant size before presentation due to its asymptomatic nature.…”

Section: Introductionmentioning

confidence: 99%

Odontogenic myxoma of the maxilla: surgical management and case report

et al. 2016

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Odontogenic Myxoma with Diffuse Calcifications: A Case Report and Review of the Literature

Cited by 28 publications

References 17 publications

Estudo retrospectivo de casos de mixoma odontogênico diagnosticados em um Serviço de Histopatologia Oral / Retrospective study of odontogenic myxoma cases diagnosed in an Oral Pathology Center

Estudo retrospectivo de casos de mixoma odontogênico diagnosticados em um Serviço de Histopatologia Oral / Retrospective study of odontogenic myxoma cases diagnosed in an Oral Pathology Center

Odontogenic myxoma: A 63‐year retrospective multicenter study of 85 cases in a Brazil population and a review of 999 cases from literature

Odontogenic myxoma of the maxilla: surgical management and case report

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