Odontogenic Fibromyxoma of the Maxilla: A Case Report and Review of the Literature

Dietrich, Eva-Maria; Papaemmanouil, Styliani; Koloutsos, Georgios; Antoniades, Hlias; Αντωνιάδης, Κωνσταντίνος

doi:10.1155/2011/238712

Cited by 29 publications

(52 citation statements)

References 37 publications

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“…The terms odontogenic myxomas and MF have often been used interchangibly in literature and only few cases have been specifically reported as odontogenic MF . These neoplasms most commonly involve posterior region of mandible, anterior part of mandible and maxilla are rarely involved . Females are more commonly affected than males .…”

Section: Discussionmentioning

confidence: 99%

Cytological findings of odontogenic myxofibroma: A diagnostic dilemma

Khare

Joshi

Majumdar

et al. 2016

Diagnostic Cytopathology

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Odontogenic myxofibroma represents a rare slow-growing benign neoplasm, which usually occurs in the second and third decades of life and rarely in children or adults over 50 years of age. Myxomas in general represent from 2.3% to 17.7% of all odontogenic tumors, and myxofibromas represent a small number of all myxomas. Limited evidence is present in literature regarding the cytological diagnosis of odontogenic myxoma/myxofibroma. We hereby report the cytomorphological features of a histologically confirmed case of odontogenic myxofibroma and the pitfalls of the cytological diagnosis. A painless jaw swelling in a young boy was aspirated. Scanty mucoid material was obtained. Cytology Smears were moderately cellular and showed a population comprising predominantly of singly scattered plump to fusiform cells with bipolar cytoplasmic processes showing mild to moderate atypia embedded within dense myxoid matrix and another population of cells arranged in clusters. Case was interpreted as low grade mesenchymal tumor. Subsequent biopsy confirmed it as odontogenic myxofibroma arising in a odontogenic keratocyst. Precise interpretation of intraosseous jaw lesions FNAC may not always be possible, but an attempt should be made to broadly classify the lesion as an inflammatory lesion, cystic lesion, giant cell lesion, fibro-osseous lesion or as an odontogenic tumor. If dual population of odontogenic epithelium and mesenchymal cells embedded in myxoid matrix are identified in such aspirates, a possibility of myxoid odontogenic tumor may be suggested. Triple correlation of cytological, clinical and radiological findings can guide the surgeon for taking appropriate therapeutic decisions.

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Section: Discussionmentioning

confidence: 99%

Cytological findings of odontogenic myxofibroma: A diagnostic dilemma

Khare

Joshi

Majumdar

et al. 2016

Diagnostic Cytopathology

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“…The term myxoma was first used by Virchow in 1863, but the term fibromyxoma was described by Dietrich et al [2]. The tumour occurs in soft and bony tissues.…”

Section: Introductionmentioning

confidence: 99%

Odontogenic Fibromyxoma of Maxilla: A Rare Case Report

Reddy

Kumar

Muppa

et al. 2013

Case Reports in Dentistry

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Fibromyxoma is a rare odontogenic tumour which is benign, but locally aggressive. The etiology of these tumours is unknown, but because of its limitation to the teeth bearing areas and occasional presence of odontogenic epithelial fragments within the tumour which suggest that it is of odontogenic origin. It is a slow growing painless tumour that frequently occurs in second and third decades of life. Females are more commonly affected than males. The tumour can cause gradual expansion of the cortical plates and cause loosening and displacement of teeth, although root resorption may be rare. The surgical treatment of these tumours consists of complete enucleation or radical excision. The aim of this paper is to present the rarity of a fibromyxoma of the maxilla.

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“…14 However, in our present case, IHC examination revealed negative for S-100 protein, suggestive of nonneural origin of the lesion. Myxomas of the jaw have a recurrence rate of 25 to 43%, which is strongly related to the nature of the lesion; without a sheath (encapsulated) and its potential for secretion of bioactive enzymes, such as hyaluronic acid and acid phosphatase, it contributes to locally infiltrative nature, 15 thus making the complete removal difficult, thereby, leading to poor prognosis. As the tumor is not radiosensitive, surgery is the only treatment of choice.…”

Section: Discussionmentioning

confidence: 99%