Odontodysplasia

Alexander, William N.; Lilly, Gilbert E.; Irby, William B.

doi:10.1016/0030-4220(66)90372-0

Cited by 27 publications

(4 citation statements)

References 5 publications

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“…The etiology remains uncertain of many possible causes that have been proposed in the literature. This included somatic mutation of the dental lamina [8], viral infection [9], medication taken during pregnancy [10], local circulating disorder like vascular nevi on the skin of the affected side of the face [11, 12], failure of migration, and differentiation of neural crest cells [2]. …”

Section: Introductionmentioning

confidence: 99%

Regional Odontodysplasia with Generalised Enamel Defect

Al-Mullahi

Toumba

2016

Case Reports in Dentistry

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Regional odontodysplasia (ROD) is uncommon developmental anomaly, which tends to be localised and involves the ectodermal and mesodermal tooth components. A five-year-old female was referred to Department of Child Dental Health at the Leeds Dental Institute regarding malformed primary teeth. On examination 64, 74, and 72 had localised hypomineralized enamel defect. The crown of 55 was broken down with only the root remaining below the gingival level. 54 has a yellowish brown discolouration with rough irregular surface. The upper anterior teeth show mild enamel opacity. Radiographically, 55 and 54 had thin radioopaque contour, showing poor distinction between the enamel and dentine and the classic feature of a wide pulp chamber. 15, 16, and 17 were developmentally delayed and were displaying the characteristic “ghost appearance.” Comprehensive dental care was done under local anaesthesia and it included extraction of the primary molars affected by ROD, stainless steel crown on 64, and caries prevention program. Fifteen months following the initial assessment the patient's oral condition remains stable and she is under regular follow-up at the department. Paediatric dentists should be aware of this anomaly as it involves both dentitions and usually requires multidisciplinary care.

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Section: Introductionmentioning

confidence: 99%

Regional Odontodysplasia with Generalised Enamel Defect

Al-Mullahi

Toumba

2016

Case Reports in Dentistry

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“…It has been suggested that this condition may derive from a disorderly proliferation of the dental epithelium at an early stage of development, during the formation of dental structures. Many etiologic factors have been suggested, such as local circulatory disorders [15][16][17][18] , viral infection of the tooth germ during development 16,17,19,20) , pharmacotherapy during pregnancy 6) , local trauma 3,15,21) , metabolic disturbances, local somatic mutation affecting the dental lamina in the area 11) , and failure of the migration of the neural crest cells 22) . Although many theories have been advanced by various authors, it was not possible to determine the precise etiological factors in our case.…”

Section: Discussionmentioning

confidence: 99%

Regional odontodysplasia: Long-term observation of a case on the mandibular left side

Iizawa

Kinjoh

Taguchi

2010

Pediatric Dental Journal

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Regional odontodysplasia is an unusual non-hereditary developmental anomaly of tooth structures in both primary and permanent dentitions. The appropriate treatment differs for each individual's clinical findings. The purpose of this study was to describe the clinical findings and the long-term progress as to the treatment and the management of a male patient who was diagnosed with regional odontodysplasia on the left side of the mandible. The mandibular left primary molars had shown a remarkable "ghost-like" appearance on x-ray, but they had already been extracted by an oral surgeon because of osteomyelitis due to pulpal infection, when the patient was referred to our pediatric dental clinic at 5 years of age. According to x-ray findings, the five permanent teeth (32,33, 34, 35, 36) on the mandibular left side were delayed in formation. During the 15 years from age 5 to age 20, the patient was treated and managed in our clinic and the prosthodontic clinic of our hospital. Because the patient lost his mandibular left primary teeth early but presented delayed eruption of succedaneous permanent teeth, the patient used a temporary removable space maintainer for a long time. Although the affected first molar was extracted, the second premolar erupted and the other three unerupted teeth were not removed. The edentulous region was rehabilitated with a removable partial acrylic prosthesis when the patient was 19 years and 4 months. It was found that a multidisciplinary approach was essential for the long-term follow-up of typical regional odontodysplasia.

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“…19 A hereditary factor can be discounted because of the lack of evidence of such a history in cases reported to date. The possibility of maternal illness, drug therapy, or both as etiologic factors was suggested by cases reported in children whose mothers had pneumonia 14 or toxemia 16 during pregnancy or who took diuretics, 20 tranquilizers, or hormones during the first trimester.…”

Section: Conflicts Of Interestmentioning

confidence: 99%