Oculometry findings in high myopia at adult age: considerations based on oculometric follow‐up data over 28 years in a cohort‐based Danish high‐myopia series

Fledelius, Hans C.; Goldschmidt, Ernst

doi:10.1111/j.1755-3768.2008.01472.x

Cited by 34 publications

(32 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A longitudinal study in highly myopic eyes in adults reported an increase in the axial length [5]. In addition, Saka et al studied the medical records of 184 eyes of 101 high myopia patients with refractive errors of −6 D or more or with axial lengths of 26.5 mm or more and reported a significant increase of the axial length from 28.6 mm to 29.4 mm over the mean follow-up period of 8.2 years [6].…”

Section: Discussionmentioning

confidence: 99%

“…However, in a recent longitudinal study by He et al, slight increase of the axial length in adults (mean refractive error, −0.44 ± 2.21 diopters) was reported [4]. Conversely, an increase in the axial length in adults with highly myopic eyes is common and has been previously shown in longitudinal studies [5–7]. However, to the best of our knowledge, there have been no studies directly comparing the increase in the axial length in adults with non-highly myopic eyes or highly myopic eyes.…”

Section: Introductionmentioning

confidence: 99%

“…However, to the best of our knowledge, there have been no studies directly comparing the increase in the axial length in adults with non-highly myopic eyes or highly myopic eyes. In addition, because previous studies on the axial length in highly myopic eyes have not compared between eyes with and without macular complications [5–7], their influence on the axial length remains unknown. Thus, we investigated how changes in the axial length differ between non-highly myopic and highly myopic eyes with or without complications, particularly CNV and MTM.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Axial length changes in highly myopic eyes and influence of myopic macular complications in Japanese adults

Ohsugi¹,

Ikuno

Shoujou³

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

PurposeTo investigate changes of the axial length in normal eyes and highly myopic eyes and influence of myopic macular complications in Japanese adults.Study designRetrospective longitudinal case series.MethodsThe changes in the axial length of 316 eyes from 316 patients (mean age, 63.8 ± 9.0 years; range, 34–82; 240 females) examined using IOLMaster with a follow-up period of at least 1 year were studied. This study included 85 non-highly myopic eyes (|refractive error| ≤ 5 diopters; 63 females; non-highly myopic group), 165 highly myopic eyes (refractive error ≤ −6 diopters or axial length ≥ 26 mm; 124 females) without macular complications (no complications group), 32 eyes (25 females) with myopic traction maculopathy (MTM group), and 34 eyes (28 females) with myopic choroidal neovascularization (CNV group).ResultsAll groups showed a significant increase in the axial length during the follow-up period (mean follow-up, 28.7 ± 16.8 months; range, 12–78) (P < 0.01). Changes in the axial length/year in the no complications group (0.041 ± 0.05 mm) were significantly greater than those in the non-highly myopic group (0.007 ± 0.02 mm) (P < 0.0001). Furthermore, changes in the CNV group (0.081 ± 0.04 mm) were significantly greater than those in the no complications (P < 0.0001) and MTM (0.040 ± 0.05 mm) (P = 0.0059) groups, whereas no significant difference was found between the changes in the MTM and no complications groups (P = 0.91). Multiple regression analyses indicated that CNV eyes (P < 0.0001) and female patients’ eyes (P = 0.04) showed greater changes in the axial length/year.ConclusionsAll groups showed an increase in the axial length, which was greater for highly myopic eyes. In particular, CNV eyes showed greater increases, indicating that larger changes in the axial length may require careful follow-up.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Axial length changes in highly myopic eyes and influence of myopic macular complications in Japanese adults

Ohsugi¹,

Ikuno

Shoujou³

et al. 2017

PLoS ONE

View full text Add to dashboard Cite

show abstract

“…Further work should be done to improve the PPV, such as including more risk factors in the prediction, i.e., history of myopic parents [24,25], environmental factors such as outdoor activity time [26,27], near work time, [28,29] and optical biometry. Further follow-up to determine progression rates may also improve predictive power[30]. One of our future directions is to incorporate these potential risk factors into our prediction method.…”

Section: Discussionmentioning

confidence: 99%

Identifying Children at Risk of High Myopia Using Population Centile Curves of Refraction

et al. 2016

View full text Add to dashboard Cite

PurposeTo construct reference centile curves of refraction based on population-based data as an age-specific severity scale to evaluate their efficacy as a tool for identifying children at risk of developing high myopia in a longitudinal study.MethodsData of 4218 children aged 5–15 years from the Guangzhou Refractive Error Study in Children (RESC) study, and 354 first-born twins from the Guangzhou Twin Eye Study (GTES) with annual visit were included in the analysis. Reference centile curves for refraction were constructed using a quantile regression model based on the cycloplegic refraction data from the RESC. The risk of developing high myopia (spherical equivalent ≤ -6 diopters [D]) was evaluated as a diagnostic test using the twin follow-up data.ResultsThe centile curves suggested that the 3rd, 5th, and 10th percentile decreased from -0.25 D, 0.00 D and 0.25 D in 5 year-olds to -6.00 D, -5.65D and -4.63 D in 15 year-olds in the population-based data from RESC. In the GTES cohort, the 5th centile showed the most effective diagnostic value with a sensitivity of 92.9%, a specificity of 97.9% and a positive predictive value (PPV) of 65.0% in predicting high myopia onset (≤-6.00D) before the age of 15 years. The PPV was highest (87.5%) in 3rd centile but with only 50.0% sensitivity. The Mathew’s correlation coefficient of 5th centile in predicting myopia of -6.0D/-5.0D/-4.0D by age of 15 was 0.77/0.51/0.30 respectively.ConclusionsReference centile curves provide an age-specific estimation on a severity scale of refractive error in school-aged children. Children located under lower percentiles at young age were more likely to have high myopia at 15 years or probably in adulthood.

show abstract

“…Highly significant correlation (p<0.001) was established between the two parameters. 38 Park et al came to the conclusion that shorter eyes i.e. eyes with increased corneal curvature show hyperopic shift while longer eyes i.e., eyes with decreased corneal curvature show myopic shift.…”

Section: Discussionmentioning

confidence: 99%

Relation of Refractive Error With Corneal Curvature of the Eye in Adult Subjects With Refractive Error

Arora¹,

Singh²,

Aneja³

et al. 2015

jemds

View full text Add to dashboard Cite

BACKGROUND:The second most common reason for blindness worldwide is refractive error. Not only is the global burden of refractive error very high, but also increasing every day. A number of associated serious complications and the various modes of treatment aspect of the refractive errors, warrants the necessity to explore the various factors that have impact on them. The present study was done with the purpose of establishing the relation of refractive error with corneal curvature of the eye in adult subjects. This study was done on one thousand eyes, of five hundred adult cases, over a total period of 2 years. The cases included were of both sex's male and female, taken from Patiala and around Patiala. The subjects were recruited on the basis of inclusion criteria: refractive error-myopia and hyperopia, aged between 20-40 years. The subjects in our study included students of M.B.B.S. (Bachelor of Medicine and Bachelor of Surgery) and B.D.S. (Bachelor of Dental Sciences) and routine OPD (outpatient door) patients falling in the range of concern of my study. The instruments used in this study were: Auto refractor and Auto keratometer for measuring refractive error and corneal curvature respectively. Each subject was explained thoroughly about the whole procedure. Their informed written consent was also taken. General examination was done in each and every case. Thereafter local examination was done and the two concerned ocular parameters were recorded. The aim was to find in the subjects the type and degree of refractive error and corneal curvature and to find the relationship in between the two parameters. Statistical analysis was done of the data obtained. The results of our present study have showed that the spherical refractive error has statistically highly significant positive correlation with corneal curvature, in right eye (r=0.159, p<0.01) and in left eye (r=0.184, p<0.01). It means that as we progress from myopic to hyperopic refractive error accordingly the corneal curvature increases. In myopia or shortsightedness, image is formed in front of retina. Increase in myopic refractive error is found to be in close association with decreased corneal curvature. In hyperopia or long sightedness, image is formed behind the retina. Increased corneal curvature of the eyeball is found to be closely associated with hyperopia.

show abstract

Oculometry findings in high myopia at adult age: considerations based on oculometric follow‐up data over 28 years in a cohort‐based Danish high‐myopia series

Cited by 34 publications

References 19 publications

Axial length changes in highly myopic eyes and influence of myopic macular complications in Japanese adults

Axial length changes in highly myopic eyes and influence of myopic macular complications in Japanese adults

Identifying Children at Risk of High Myopia Using Population Centile Curves of Refraction

Relation of Refractive Error With Corneal Curvature of the Eye in Adult Subjects With Refractive Error

Contact Info

Product

Resources

About