“…1 , 2 Well-known in the pediatric ophthalmology and anesthesiology literature, this reflex has also been reported in a variety of adult surgeries including maxillofacial surgeries involving the maxillary and mandibular distributions of the trigeminal nerve, skull base surgeries, and even surgery involving an empty orbit. 3 , 4 , 5 The OCR has also been described in the setting of trauma, most commonly associated with trapdoor fractures involving entrapment of an extraocular muscle. 6 , 7 Here we describe a case of the OCR resulting in autonomic instability elicited by total globe dislocation through a large orbital floor fracture.…”