Oculo-Oscillo-Dynamography: A Diagnostic Procedure for Recording Ocular Pulses and Measuring Retinal and Ciliary Arterial Blood Pressures

Ulrich, W.-D.; Ulrich, Ch.

doi:10.1159/000265391

Cited by 53 publications

(35 citation statements)

References 7 publications

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“…15 With this technique, a suction cup (diameter 11 mm) is applied to the temporal sclera just posterior to the limbus. It produces a negative pressure that is transferred onto the globe and induces a subsequent increase in IOP.…”

Section: Methodsmentioning

confidence: 99%

Effects of change in intraocular pressure on axial eye length and lens position

Leydolt

Findl

Drexler

2007

Eye

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Purpose To quantify the biometric changes of ocular dimensions with mechanical elevation of intraocular pressure (IOP) in vivo, to get a better understanding of the elastic properties of the human ocular structures that may play a role in the pathogenesis of various diseases such as myopia or glaucoma. Methods Changes in IOP were induced by a suction cup in 18 eyes under cycloplegia. Axial eye length (AEL) and anterior chamber depth (ACD) were measured with non-invasive laser interferometry during elevation of the IOP 10 and 20 mmHg over baseline values and after a 10-min resting period. Results IOP elevation of 10 and 20 mmHg respectively caused a significant increase of AEL of 23 lm (95% confidence interval: 14-34 lm) and 39 lm (confidence interval (CI): 28-51 lm). After mechanical oculopression, which resulted in an IOP reduction of -5.1 mmHg (CI: À6.3 to À4.0 mmHg) vs baseline, a significant shortening of À7 lm (CI: À13 to 0 lm) was observed. The change in AEL correlated with the change in IOP (r ¼ 0.66, P ¼ 0.005). Furthermore, a significant increase in ACD of 30 lm (CI: 24-36 lm) was detected with IOP reduction after oculopression, but no change was seen during IOP elevation. Conclusions Biometric changes of the human eye as a response to IOP changes were assessed in vivo. The correlation between change in AEL and IOP found emphasizes the need of in vivo ocular rigidity measurements in the human eye.

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Section: Methodsmentioning

confidence: 99%

Effects of change in intraocular pressure on axial eye length and lens position

Leydolt

Findl

Drexler

2007

Eye

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“…The IOP was raised applying a method described by Ulrich and Ulrich. 35 In our study we used an automatic suction pump that is connected by plastic tubing to a rigid plastic suction cup. After topically applied local anesthesia, a standardized 11 mm diameter suction cup was placed on the temporal sclera with the anterior edge at least 1 mm from the limbus.…”

Section: Measurementsmentioning

confidence: 99%

Comparison of Choroidal and Optic Nerve Head Blood Flow Regulation during Changes in Ocular Perfusion Pressure

Schmidl¹,

Boltz

Kaya³

et al. 2012

Invest. Ophthalmol. Vis. Sci.

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PURPOSE. We compared the response of choroidal and optic nerve head blood flow (ChBF, ONHBF) in response to an increase in ocular perfusion pressure (OPP) during isometric exercise and during a decrease in OPP during an artificial increase in intraocular pressure (IOP). METHODS.We included 96 healthy subjects in our study. In 48 subjects OPP was increased by 6 minutes of squatting, and either ONHBF (n ¼ 24) or ChBF (n ¼ 24) was measured continuously. In 48 other healthy subjects either ONHBF (n ¼ 24) or ChBF (n ¼ 24) was measured continuously during a period of artificial increase in IOP using a suction cup. All blood flow measurements were done using laser Doppler flowmetry. RESULTS.During all experiments the response in blood flow was less pronounced than the response in OPP, indicating for flow regulation. During isometric exercise ChBF regulated better than ONHBF (P ¼ 0.023). During artificial IOP increase ONHBF regulated better than ChBF (P ¼ 0.001). Interindividual variability in blood flow responses was high. During squatting ONHBF decreased considerably below baseline ONHBF when OPP fluctuated in 3 subjects, although OPP still was much higher than at baseline. This phenomenon was not observed in the choroid. CONCLUSIONS.Our data indicate that regulation of ChBF and ONHBF during changes in OPP is different and complex. In some subjects performing squatting, considerable ONHBF reductions were observed during OPP fluctuations, although OPP still was high. Whether this predisposes to ocular disease remains unclear. (Invest Ophthalmol Vis Sci. 2012;53:4337-4346)

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“…The design and function of the ocular pneumoplethysmograph (OPG) closely parallels that of the oculo-oscillodynamograph (OODG) [1][2][3]. While the OPG has been used primarily for assessing the physiology of the carotid-ophthalmic arterial axis in relation to carotid lesions of hemodynamic consequence, the focus of the OODG has been the characterization of ocular hemodynamics associated with diseases intrinsic to the eye and to the evaluation of the effects of ocular treatment regimens.…”

Section: Introductionmentioning

confidence: 99%

Ocular Volume Change per Minute with Ocular Pneumoplethysmography

Gee

Reed²

1999

Ophthalmic Res

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Ocular pneumoplethysmography was performed before and after 1,737 carotid endarterectomies, 82% of which were performed for carotid lesions of hemodynamic consequence. Preoperative ocular hypoperfusion without ischemia was associated with at least transient postoperative ocular hyperemia. A difference in ocular volume change per minute of 14.0%, female greater than male, was explained by sex differences in heart rate, brachial pulse pressure and eye size. These observations may have a direct application in the management of diabetic retinopathy with panretinal photocoagulation.

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Oculo-Oscillo-Dynamography: A Diagnostic Procedure for Recording Ocular Pulses and Measuring Retinal and Ciliary Arterial Blood Pressures

Cited by 53 publications

References 7 publications

Effects of change in intraocular pressure on axial eye length and lens position

Effects of change in intraocular pressure on axial eye length and lens position

Comparison of Choroidal and Optic Nerve Head Blood Flow Regulation during Changes in Ocular Perfusion Pressure

Ocular Volume Change per Minute with Ocular Pneumoplethysmography

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