Ocular Toxoplasmosis

Cunningham, Emmett T.; Belfort, Rubens; Muccioli, Cristina; Arévalo, J. Fernando; Zierhut, Manfred

doi:10.3109/09273948.2015.1051360

Cited by 9 publications

(4 citation statements)

References 38 publications

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“…Although reliable information was obtained through UWF-SLO, there are differential diagnosis which may cause difficulties in individual cases. Even though OT typically presents as an isolated focus of retinochoroiditis [3], atypical presentations may occur [37]. Several clinical features may resemble OT, and these may include retinochoroidal scars due to focal laser photocoagulation treatment (Fig.…”

Section: Discussionmentioning

confidence: 99%

Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis

et al. 2021

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Purpose Studies on the occurrence of ocular toxoplasmosis (OT) in a general population are rare. Therefore, we conducted this pilot study to assess whether a nonmydriatic ultra-wide-field (UWF) scanning laser ophthalmoscope (SLO) is suitable for a simple, rapid screening procedure. Methods The population of this cross-sectional study was randomly recruited from a cohort of hospital-based patients in an urban geriatric hospital. Ophthalmologic evaluation was performed on 201 eyes from 101 participants through nonmydriatic UWF-SLO (Optos Daytona) and assessed for suspicious lesions and other relevant ocular findings. All images were evaluated by two independent examiners. Individuals who presented lesions with a morphological appearance suggestive of OT underwent fundoscopy and serological analysis of Toxoplasma gondii-specific antibodies. Results The mean age of the study group was 76 years, and 63 (62%) were female. Despite many health restrictions, the SLO examination was carried out easily in this geriatric population. Three participants presented findings by SLO suspicious for T. gondii-related injury. Further clinical examination and serological investigation confirmed the diagnosis, with funduscopic evaluation and positive T. gondii ELISA testing. In addition, a high rate of arterial hypertension and dyslipidemias within the cohort led to a high incidence of vascular changes and age-related fundus findings. Conclusion In our study, we confirm that UWF-SLO technology is helpful in the rapid detection of peripheral retinal injuries in elderly patients such as OT and may be used as a routine screening tool.

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Section: Discussionmentioning

confidence: 99%

Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis

et al. 2021

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“…The involvement of the underlying choroid is termed “choroidoretinitis” and describes the clinical image. Ocular complications include choroidal neovascularization, cataract, glaucoma, optic nerve atrophy, and retinal detachment ( 6 , 7 ).…”

Section: Discussionmentioning

confidence: 99%

The Role of Corticosteroids in Treating Acute Ocular Toxoplasmosis in an Immunocompetent Patient: A Case Report

Lin

Lee

2022

Front. Med.

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BackgroundThis study aimed to report a case who was treated with corticosteroids and anti- parasitic agents for ocular toxoplasmosis, but who progressed to acute retinal necrosis, and finally retinal detachment.Case PresentationA 42-year-old man presented to the ophthalmology clinic with a 1-month history of progressive blurred vision and floaters in his right eye. His best visual acuity (VA) was 20/20 in both eyes. The anterior segment was unremarkable. Funduscopic examination of the right eye revealed active lesions of whitish foci of chorioretinitis with surrounding edema along the superonasal vessels, and retinal vasculitis with perivascular sheathing. Serologic testing was positive for Toxoplasma gondii IgM and IgG, but negative for other virus- and syphilis infections. Ocular toxoplasmosis was diagnosed. Corticosteroids and anti-parasitic agents were given simultaneously, but his right eye VA became 20/100. Funduscopic examination revealed retinal necrosis with localized retinal breaks. We immediately performed focal photocoagulation, however, his right eye progressed to retinal detachment and required vitrectomy.ConclusionEarly administration of systemic corticosteroids in patients with acquired acute ocular toxoplasmosis may lead to complications that impair vision. Intensive observation should be arranged after corticosteroid use.

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“…After ingestion, oocysts liberate sporozoites, which penetrate intestinal mucosa and reach to distant organs such as brain, eyes, liver, spleen, lymph nodes, heart, skeletal muscles and placenta by blood and lymphatic stream. Toxoplasma tissue cysts also occur in the skeletal muscles of the intermediate host such as sheep and pigs ( Figure 2) [54]. In addition, developing fetus can acquire the infection transplacentally from the mother during pregnancy.…”

Section: Toxoplasmosismentioning

confidence: 99%

Ocular Parasitic Infections – An Overview

Malla¹,

Goyal²

2016

Advances in Common Eye Infections

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Eyes are said to be the windows of body, by which this beautiful world is visualized. Human eye has a unique structure and is vulnerable to numerous infections. Whenever anatomical structures are breached, host defenses come into play, but if infection is severe and not treated timely, it could lead to visual impairment or blindness. Parasitic infections are considered, the significant causes of ophthalmic diseases worldwide. In this chapter, an overview of ocular parasitic infections (OPI) is detailed out, with an initial brief introduction followed by description of anatomy of the human eye and various defense mechanisms to provide better understanding of the parasitic infections affecting different parts of human eye. The last part includes individual details of various human ocular parasitic infections. Ocular infections can be classified based on either the etiological agent or according to the anatomical site of infection. The parasitic etiological agents include mainly protozoa, helminths and ectoparasites. Due to the complex life cycles of parasites and their tendency to cause wide range of pathologic lesions, different parasites/parasitic infections have been addressed separately, including brief epidemiology, clinical features, diagnosis and treatment.

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Ocular Toxoplasmosis

Cited by 9 publications

References 38 publications

Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis

Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis

The Role of Corticosteroids in Treating Acute Ocular Toxoplasmosis in an Immunocompetent Patient: A Case Report

Ocular Parasitic Infections – An Overview

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