Ocular Symptoms in Febrile Mucocutaneous Reactions (Ectodermosis Erosiva Pluriorificialis, Stevens‐johnson's Syndrome, Mucocutaneous‐ocular Syndrome Etc.)

A Clinical Study on Acute Ophthalmic Manifestation and Management of Stevensjohnson Syndrome Conducted at a Tertiary Centre of Thiruvananthapuram, Kerala

“…In the acute stage, catarrhal type of conjunctivitis was the commonest and was manifested in 50% study population. This is in concordance with the findings of a study conducted by different investigators like Duggan and Gaines (1951), 8 Howard (1963) 17 and Storm (1966) 4 in which at least 10% showed mucopurulent conjunctivitis.…”

“…Data from surveillance network cited by Roujeau et al (1995) 1 on 245 people hospitalised for SJS reported risk factors was oral intake of 80% NSAIDS and similar observations were also reported by Storm (1966). 4 But in this study, Brufen contributes only (5.8%) as an aetiological factor and also mentioned about new users of antiepileptic adverse reactions as an aetiological factor. In the present study, antiepileptic contributes 19.2%.…”

“…3 A significant majority of patients with Acute SJS/ TEN will have ophthalmic pathology. According to Storm (1996), 4 he found that eyes are very often affected 93% and called it as a mucocutaneous ocular fever. Studies by Power et al (2007) 5 and Chang et al (2011) 6 reported ocular involvement in 69% and 81% respectively of patients with SJS and TEN.…”

“…Commonest type of conjunctivitis is the catarrhal type. But few authors (Duggan and Gaines, 1951;Howard, 1963;Strom, 1966) 8,17,4 states purulent conjunctivitis and pseudomembranous were the commonest manifestations. Misra and Chandi Das (1968) 18 described a case of SJS with severe bilateral congestion of bulbar and tarsal congestion of conjunctivae with profuse mucopurulent discharge.…”

“…This was in correspondence with the findings of a study conducted by Duggan and Gaines (1951), 8 Howard (1963) 17 and Storm (1966). 4…”