Ocular Scrofuloderma with Unilateral Proptosis

Sardana, Kabir; Koranne, R V; Langan, Usha; Sharma, R. C.; Bhatnagar, Shishir Kumar

doi:10.1111/j.1346-8138.2002.tb00255.x

Cited by 18 publications

(8 citation statements)

References 10 publications

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“…This was at variance with our study, in which molluscum contagiosum and viral exanthema were seen commonly, consistent with another study from India (13). Being an endemic country for mycobacterial diseases, patients with leprosy and tuberculosis were observed with some unusual presentations (17) unlike other studies (1,2,4,5,7,10,11,14).…”

Section: Discussionmentioning

confidence: 76%

The Spectrum of Skin Disease Among Indian Children

Sardana

Mahajan

Sarkar

et al. 2009

Pediatric Dermatology

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104

103

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Skin diseases in children are encountered frequently and their characterization is essential for the preparation of academic, research and health plans. A retrospective study was designed to evaluate the epidemiologic features of pediatric dermatoses in India. The setting was a tertiary care referral center in India (Kalawati Saran Children's Hospital, New Delhi) during January 1997 to December 2003. A total of 30,078 children less than 12 years of age with 32,341 new dermatoses were recorded, with a male to female ratio of 1.07:1. Most of the disease was seen in the 1- to 5-year age group (44.94%). The most common skin diseases were infections and infestations (47.15%) consisting of bacterial infections (58.09%) and scabies (21.54%), followed by eczemas (26.95%), infantile seborrheic dermatitis, scabies, and pityriasis alba. Other unique dermatoses in our settings were papular uticaria (3.59%), miliaria (5.46%), postinflammatory pigmentary abnormalities (1.68%), and nutritional deficiency dermatoses (0.45%). A majority of patients were diagnosed clinically and special diagnostic tests were conducted in 2.6% of patients. The most common diagnostic test used was KOH mount (59.2%), followed by skin biopsy (39%). Nearly 90% of patients were seen without any referral and in the remaining, a majority were referred by pediatricians (75%). A majority of patients were diagnosed to have infection followed by dermatitis in our setting.

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Section: Discussionmentioning

confidence: 76%

The Spectrum of Skin Disease Among Indian Children

Sardana

Mahajan

Sarkar

et al. 2009

Pediatric Dermatology

Self Cite

104

103

View full text Add to dashboard Cite

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“…It often occurs in children and patients with low immunity and involves most commonly the lymph nodes of the cervical region. There have been reports of ocular scrofuloderma with unilateral4 as well as bilateral5 orbital tuberculosis presenting with proptosis.…”

Section: Discussionmentioning

confidence: 99%

“…Ocular involvement is well described in association with cutaneous tuberculosis; most reports documented are phlyctenular keratoconjunctivitis, tarsitis, and orbital tuberculosis 3. Ocular scrofuloderma with orbital involvement has been previously described 45. However, to the best of our knowledge, no case of bilateral simultaneous symmetrical multiple corneal ulceration with perforation has been reported in the English peer review literature.…”

Section: Introductionmentioning

confidence: 93%

Scrofuloderma and bilateral anterior staphyloma of eye: An unusual association

Kandar

Sinha

Sharma

et al. 2011

Middle East Afr J Ophthalmol

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We report a patient with bilaterally symmetrical perforated corneal ulcers with formation of anterior staphyloma associated with scrofuloderma. A 22-year-old female in her third month postpartum presented with multiple perforated corneal ulcers bilaterally. There was a presence of a skin lesion that was consistent with scrofuloderma. Fine needle aspiration cytology of preauricular lymph nodes showed evidence of granulomatous inflammation consistent with tuberculosis. Corneal scraping revealed the presence of coagulase-negative Staphylococcus. She was treated with topical fortified combination antibiotics (cefazolin and tobramycin). The corneal ulcer resolved with formation of anterior staphyloma in both eyes. The patient underwent anterior staphylectomy and tectonic keratoplasty in both eyes. Eight weeks postoperatively, her visual acuity improved to 20/200 in both eyes with clear grafts. Scrofuloderma may be associated with recurrent phlyctenulosis. Multiple corneal ulcerations coupled with use of topical steroids may result in corneal perforation and formation of anterior staphyloma.

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“…Many of the cases of anterior segment ocular involvement are not associated with systemic manifestations of tuberculosis and appear to be localized to the eye [7] commonly with negative chest radiograph. Tuberculosis of the neck known as 'scrofula' [7,36] may present with cervical lymphadenopathy and if untreated may lead to cutaneous fistula and drainage.…”

Section: Ocular Manifestations Of Tuberculosismentioning

confidence: 99%