Ocular Response to Lens Care Systems in Adolescent Soft Contact Lens Wearers

Soni, P. Sarita; Horner, Douglas G.; Ross, J

doi:10.1097/00006324-199602000-00002

Cited by 32 publications

(33 citation statements)

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“…Estimates of the prevalence of idiopathic staining in non-contact lens wearers vary widely due to differences in subject selection, study methodology and observer training and criteria [39], yet there is some evidence to suggest that the staining we observed more than 24 h after discontinuation may not be simply "normal" staining unrelated to long-term lens wear. Although some estimates of the prevalence of idiopathic staining in non-CL wearers are as high as 79% [40], other studies have reported prevalences ranging from 0% to 19% [41][42][43], compared with the approximately 39% of subjects with corneal staining in the current study. Due to the large size of our database, we can speculate that this excess prevalence of corneal staining, over and above the prevalence of idiopathic staining seen in non-contact lens wearers, and which was not the result of transient insult to the corneal surface due to lens wear within 24 h, is due to a changing ocular surface observable by clinicians from long-term contact lens wear.…”

Section: Discussioncontrasting

confidence: 76%

Ethnic differences in dry eye symptoms: Effects of corneal staining and length of contact lens wear

Tran

Graham

Lin

2013

Contact Lens and Anterior Eye

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a b s t r a c tPurpose: To explore the relationships among length of contact lens (CL) wear, degree of corneal staining and severity of dryness symptoms, and to determine whether these relationships differ between Asians and non-Asians. Methods: Adapted soft CL wearers (n = 395; 180 Asian, 215 non-Asian) were required to discontinue CL wear for at least 24 h and report to the University of California, Berkeley Clinical Research Center (UCB-CRC). Fluorescein corneal staining was graded according to Brien Holden Vision Institute scales. Length of CL wear was reported by subjects and subjective dryness ratings were collected using the UCB-CRC Dry Eye Flow Chart (DEFC). Results: More Asian CL wearers exhibited corneal staining compared to non-Asians, and Asian CL wearers had a higher mean grade of corneal staining (p < 0.001), as well as a higher mean DEFC classification (p < 0.001). The difference between Asians and non-Asians in grades of corneal staining extent and depth were significant (p < 0.001). Among non-Asian CL wearers, dryness symptoms decreased with more years of CL wear and increased in the presence of corneal staining, which was not the case for Asian CL wearers. Conclusions: Asian soft CL wearers reported more severe dryness symptoms and demonstrated more severe corneal staining overall compared to non-Asians. Among non-Asians, dryness symptoms were less severe on average with increased years of CL wear and more severe in the presence of corneal staining. Dryness severity does not appear to be related to years of CL wear or corneal staining among Asians.

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Section: Discussioncontrasting

confidence: 76%

Ethnic differences in dry eye symptoms: Effects of corneal staining and length of contact lens wear

Tran

Graham

Lin

2013

Contact Lens and Anterior Eye

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“…Thus in the study of Korb and Korb (1970), the prevalence would rise from 37% to 58% if those with staining regarded to be clinically nonsignificant, were included. They noted that, in other reports, the prevalence of staining was lower in adolescents (Soni et al, 1996) and higher in older subjects (Norn, 1970).…”

Section: Fluorescein Sodiummentioning

confidence: 74%

“…Ordinarily, a proportion of corneas in normal subjects show a low level of punctate staining immediately after fluorescein instillation (Norn, 1962(Norn, , 1964Korb and Korb, 1970;Korb and Herman, 1979;Josephson and Caffery, 1988;Caffery and Josephson, 1991;Lloyd, 1992;Wilson and Ren, 1995;Soni and Horner, 1996;Schwallie et al, 1957;Thomas et al, 1997;Dundas et al, 2001), which may be considered to be a physiological event. It is also recorded on the tarsal conjunctiva (21%) and on the caruncle (Norn, 1964).…”

Section: Fluorescein Sodiummentioning

confidence: 99%

Clinical staining of the ocular surface: Mechanisms and interpretations

Bron

Argüeso

İrkeç

et al. 2015

Progress in Retinal and Eye Research

134

109

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“…Among the many conditions it has been recorded with are meibomian gland dysfunction and marginal blepharitis, 1 conjunctivitis, 2-4 contact lens wear, 5,6 cosmetics, 7 hypertension, diabetes, 8 acute angle-closure glaucoma, autoimmune disease, chemical injury, 9,10 episcleritis, uveitis, 9,11 sickle cell disease, 12 and pharmaceutical drug use. 13 Clinical grading scales that allow the assessment of severity have been developed for many ocular conditions, including the anterior chamber angle, 14 iris neovascularisation, 15 retinal nerve fibre layer atrophy, 16 focal narrowing of retinal arterioles in glaucoma, 17 diabetic retinopathy, 18 hypertensive arteriosclerosis, 19 tarsal abnormalities, 20 and lens opacities.…”

Section: Introductionmentioning

confidence: 99%

How red is a white eye? Clinical grading of normal conjunctival hyperaemia

Murphy

Lau

Sim

et al. 2006

Eye

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Purpose To quantify the level of normal bulbar conjunctival hyperaemia using the Cornea and Contact Lens Research Unit (CCLRU) grading scale, and to investigate inter-observer agreement. Methods Bulbar conjunctival hyperaemia was assessed by two trained observers, using the CCLRU grading scale (zero to four units) interpolated into 0.1 increments, on the right eye of 121 healthy, non-contact lens-wearing subjects (male ¼ 58, female ¼ 63, median age ¼ 28 years, range 16-77). The eye was observed using a slit-lamp bio-microscope ( Â 10 magnification) under diffuse, white illumination. The subject's position of gaze was directed to allow grading of four quadrants: superior, nasal, inferior, and temporal conjunctiva. Bulbar redness was defined as the average of those four grades of conjunctival hyperaemia. A further twenty subjects were recruited to assess interobserver agreement (male ¼ 8, female ¼ 12, median age ¼ 23 years). Results The average bulbar redness was 1.93 (70.32 SD) units. The nasal (2.370.4) and temporal (2.170.4) quadrants were significantly redder than the superior (1.670.4) and inferior (1.770.4) quadrants (Po0.0001). Males had redder eyes than females by 0.2 units. Inter-observer 95% limits of agreement for bulbar redness was 0.38 units. Conclusions The average bulbar redness of 1.9 units was higher than expected, reflecting the design of the grading scale. A bulbar redness of greater than 2.6 units may be considered abnormal, and a change in bulbar redness of Z0.4 units may be significant.

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Ocular Response to Lens Care Systems in Adolescent Soft Contact Lens Wearers

Cited by 32 publications

References 0 publications

Ethnic differences in dry eye symptoms: Effects of corneal staining and length of contact lens wear

Ethnic differences in dry eye symptoms: Effects of corneal staining and length of contact lens wear

Clinical staining of the ocular surface: Mechanisms and interpretations

How red is a white eye? Clinical grading of normal conjunctival hyperaemia

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