Abstract:Purpose
Animal models have demonstrated the role of dopamine in regulating axial elongation, the critical feature of myopia. Because frequent delivery of dopaminergic agents via peribulbar, intravitreal, or intraperitoneal injections is not clinically viable, we sought to evaluate ocular penetration and safety of the topically applied dopaminergic prodrug etilevodopa.
Methods
The ocular penetration of dopamine and dopaminergic prodrugs (levodopa and etilevodopa) were qu… Show more
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