Ocular Neuromyotonia in Graves Dysthyroid Orbitopathy

Cyclic (alternate day) vertical deviation—possible forme fruste of ocular neuromyotonia

“…These closely resemble the episodic hypotropia caused by ocular neuromyotomia in Graves' disease described by Chung and colleagues. 24 Two of our cyclic cases in this series had thyroid eye disease.…”

Cyclic (alternate day) vertical deviation—possible forme fruste of ocular neuromyotonia

“…These closely resemble the episodic hypotropia caused by ocular neuromyotomia in Graves' disease described by Chung and colleagues. 24 Two of our cyclic cases in this series had thyroid eye disease.…”

Oculomotor Paresis with Cyclic Spasms: Description of Four Cases and Hypothesis of the Mechanism

“…The diagnose Oculomotor nerve paresis with cyclic spasms should be differentiated from some diseases, such as ocular neuromyotonia [2,[4][5][6][7], brain trauma [8], tumor, inflammation [8] or aneurysm [5], ocular myasthenia, demyelinating diseases, Graves disease, migraine, or intracranial hypertension. Spontaneous, brief, recurrent unilateral oculomotor nerve palsies lasting from 30 seconds to 4 hours over the period of 2 to 4 years have been reported in 3 otherwise normal individuals.…”

The Mystery of the Locking Eye

“…Ocular neuromyotonia may be seen as a delayed complication of radiation treatment, tumors, thyroid eye disease, or vascular irritation . The mechanism by which ocular neuromyotonia occurs is unclear but may relate to ephaptic stimulation of the affected cranial nerve, whereby axons are depolarized via nonsynaptic stimulation .…”

Cyclic (alternate day) vertical deviation—possible forme fruste of ocular neuromyotonia

“…These closely resemble the episodic hypotropia caused by ocular neuromyotomia in Graves' disease described by Chung and colleagues. 24 Two of our cyclic cases in this series had thyroid eye disease.…”

Oculomotor Paresis with Cyclic Spasms: Description of Four Cases and Hypothesis of the Mechanism

“…The diagnose Oculomotor nerve paresis with cyclic spasms should be differentiated from some diseases, such as ocular neuromyotonia [2,[4][5][6][7], brain trauma [8], tumor, inflammation [8] or aneurysm [5], ocular myasthenia, demyelinating diseases, Graves disease, migraine, or intracranial hypertension. Spontaneous, brief, recurrent unilateral oculomotor nerve palsies lasting from 30 seconds to 4 hours over the period of 2 to 4 years have been reported in 3 otherwise normal individuals.…”

The Mystery of the Locking Eye

“…Ocular neuromyotonia may be seen as a delayed complication of radiation treatment, tumors, thyroid eye disease, or vascular irritation . The mechanism by which ocular neuromyotonia occurs is unclear but may relate to ephaptic stimulation of the affected cranial nerve, whereby axons are depolarized via nonsynaptic stimulation .…”

Cyclic (alternate day) vertical deviation—possible forme fruste of ocular neuromyotonia

“…These closely resemble the episodic hypotropia caused by ocular neuromyotomia in Graves' disease described by Chung and colleagues. 24 Two of our cyclic cases in this series had thyroid eye disease.…”

Oculomotor Paresis with Cyclic Spasms: Description of Four Cases and Hypothesis of the Mechanism

“…The diagnose Oculomotor nerve paresis with cyclic spasms should be differentiated from some diseases, such as ocular neuromyotonia [2,[4][5][6][7], brain trauma [8], tumor, inflammation [8] or aneurysm [5], ocular myasthenia, demyelinating diseases, Graves disease, migraine, or intracranial hypertension. Spontaneous, brief, recurrent unilateral oculomotor nerve palsies lasting from 30 seconds to 4 hours over the period of 2 to 4 years have been reported in 3 otherwise normal individuals.…”

The Mystery of the Locking Eye

“…Ocular neuromyotonia may be seen as a delayed complication of radiation treatment, tumors, thyroid eye disease, or vascular irritation . The mechanism by which ocular neuromyotonia occurs is unclear but may relate to ephaptic stimulation of the affected cranial nerve, whereby axons are depolarized via nonsynaptic stimulation .…”