Ocular myasthenia

Abstract

Myasthenia gravis is a chronic autoimmune neuromuscular disorder typically presenting with variable skeletal muscle fatigue. The most prevalent initial manifestation of myasthenia is ocular myasthenia. Approximately 50% of all myasthenia cases begin with the weakening of the eye muscles that generally presents as diplopia and/or ptosis. However, about 60% of these cases progress to a generalized type within the first 2 years. The diagnosis of ocular myasthenia is often difficult but is collectively confirmed by clinical evaluation and laboratory results.Clinical manifestations, diagnostic approach, relevance, and therapeutic options are discussed in this article.