Abstract:Both spatial and temporal cues determine the fate of immature neurons. A major challenge at the interface of developmental and systems neuroscience is to relate this spatiotempo-ral trajectory of maturation to circuit-level functional organization. This study examined the development of two ocular cranial motor nuclei (nIII and nIV), structures in which a motoneuron’s identity, or choice of muscle partner, defines its behavioral role. We used retro-orbital dye fills, in combination with fluorescent markers for… Show more
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