Ocular manifestations in dengue fever

Pek, Don C.K.; Teoh, Stephen C.

doi:10.3129/i07-129

Cited by 3 publications

(3 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 Recent articles have highlighted a variety of ocular manifestations associated with dengue infection, including macular and retinal hemorrhages, 42,43 maculopathy, 44,45 optic neuritis and neuropathy, 46 vasculitis, 47 uveitis, 48 retinal artery occlusion, 49 venular occlusion, 50 and retinal and macular edema. 43,47 In a recent prospective study from Singapore, Seet and colleagues 51 observed "clinically significant" ocular symptoms, defined as symptoms severe enough to warrant referral to an ophthalmologist, in 18% of hospitalized patients with serologically confirmed dengue. A 2006 study from India examined 134 consecutive hospitalized dengue patients and discovered ocular findings on funduscopic examination in over 40%.…”

Section: Discussionmentioning

confidence: 99%

Clinical and Laboratory Features That Differentiate Dengue from Other Febrile Illnesses in an Endemic Area—Puerto Rico, 2007–2008

Gregory¹,

Santiago²,

Argüello³

et al. 2010

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

Dengue infection can be challenging to diagnose early in the course of infection before severe manifestations develop, but early diagnosis can improve patient outcomes and promote timely public health interventions. We developed age-based predictive models generated from 2 years of data from an enhanced dengue surveillance system in Puerto Rico. These models were internally validated and were able to differentiate dengue infection from other acute febrile illnesses with moderate accuracy. The accuracy of the models was greater than either the current World Health Organization case definition for dengue fever or a proposed modification to this definition, while requiring the collection of fewer data. In young children, thrombocytopenia and the absence of cough were associated with dengue infection; for adults, rash, leucopenia, and the absence of sore throat were associated with dengue infection; in all age groups, retro-orbital pain was associated with dengue infection.

show abstract

Section: Discussionmentioning

confidence: 99%

Clinical and Laboratory Features That Differentiate Dengue from Other Febrile Illnesses in an Endemic Area—Puerto Rico, 2007–2008

Gregory¹,

Santiago²,

Argüello³

et al. 2010

The American Society of Tropical Medicine and Hygiene

View full text Add to dashboard Cite

show abstract

“…MLT presented many signals described in previous works as cotton-wool spots and retinal ischemic alterations [7,8,10,14,17]. The pathogenesis of ocular manifestations is unknown, but it is probable that they are caused by increased vascular permeability involved in dengue fever pathophysiology and postviral immune reaction after thrombocytopenic state [4,6,7,14,17,43,44].…”

Section: Discussionmentioning

confidence: 98%

Dengue maculopathy: visual electrophysiology and optical coherence tomography

et al. 2009

View full text Add to dashboard Cite

The objective of this study was to evaluate the visual loss due to dengue fever using retinal and cortical electrophysiology and retinal imaging. The participants were three female patients with low visual acuity after dengue fever. They were evaluated by routine ophthalmological investigations, transient pattern electroretinogram (tPERG), transient pattern visual evoked cortical potential (tPVECP), and retinal optical coherence tomography (retinal OCT). tPERG and tPVECP amplitude (microV) and implicit time (ms) were the parameters evaluated using OCT retinal thickness (microm) and reflectivity. All patients presented low visual acuity and scotomata with or without changes in the oculus fundus. tPERG from two patients showed decreased amplitude or absence of the main components; it was not possible to record a reliable response in the third patient due to excessive blinking. tPVECP at 0.5 cpd was normal in all three patients, while at 2 cpd the main components were absent in one patient and normal in the other two patients. OCT image was abnormal in two patients, one of them with high reflectance areas and another with decreased retinal thickness (the third patient was not studied with this technique).The dengue fever can lead to visual impairment detectable by ophthalmological exams such as angiography, retinography, and OCT imaging, as well as retinal and cortical electrophysiology. Dengue maculopathy which could be caused by vascular alterations and/or aberrant immune response after infection may result in temporary or permanent visual losses.

show abstract

“…Dengue fever is a disease caused by an arbovirus transmitted by the Aedes aegypti and A. albopictus mosquito, which is endemic to Southeast Asia and Southeast Africa [ 26 ]. Dengue fever rarely affects the eye.…”

Section: Discussionmentioning

confidence: 99%

Case series of neuroretinitis in Korea

Choi,

Byon,

Kwon

et al. 2024

BMC Ophthalmol

View full text Add to dashboard Cite

Background To present the clinical characteristics of neuroretinitis in Korea. Methods Twelve patients with neuroretinitis between January 2009 and September 2020 were retrospectively reviewed. Neuroretinitis was diagnosed based on fundus findings, optical coherence tomography, and fluorescein angiography. The serological findings of each patient were reviewed. Results Fifteen eyes of 12 patients (9 male and 3 female), with a mean age of 46.0 ± 10.7 years were included. Of the nine patients who underwent serological testing for Toxocara antibodies, six (66.6%) were positive. One patient had high titers of Toxoplasma immunoglobulins M and G. One patient diagnosed with dengue fever was suspected to have neuroretinitis in both eyes. There were no related abnormalities in the serological findings in four patients (33.3%) out of 12 patients. There were no suspected cases of cat-scratch disease. The six patients who were positive for Toxocara antibodies were older (mean age: 54.5 ± 9.1 years) than the others (mean age: 37.5 ± 4.4 years, p = 0.004). The four patients without any abnormal serological findings were relatively younger (mean age: 35.7 ± 3.0 years) than the other 8 patients (mean age: 51.1 ± 10.1 years, p = 0.008). Conclusions Two-thirds of neuroretinitis patients were seropositive for Toxocara in the current cohort from Koreans. Causative factors in cases of neuroretinitis may vary according to age and region.

show abstract

Ocular manifestations in dengue fever

Cited by 3 publications

References 1 publication

Clinical and Laboratory Features That Differentiate Dengue from Other Febrile Illnesses in an Endemic Area—Puerto Rico, 2007–2008

Clinical and Laboratory Features That Differentiate Dengue from Other Febrile Illnesses in an Endemic Area—Puerto Rico, 2007–2008

Dengue maculopathy: visual electrophysiology and optical coherence tomography

Case series of neuroretinitis in Korea

Contact Info

Product

Resources

About