Ocular manifestations and MRI findings in a case of methanol poisoning

Yang, Chi; Tsai, Wen-Chuan; Lirng, Jiing Feng

doi:10.1038/sj.eye.6701641

Cited by 21 publications

(17 citation statements)

References 8 publications

(8 reference statements)

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“…3,4,7,10 Y12 In the subacute phase of methanol intoxication, putaminal and subcortical lesions demonstrate contrast enhancement, indicating the disruption of the brain-blood barrier. 7,11,12 There are only a few case reports in the literature describing DW imaging findings in methanol intoxication. 9 …”

Section: Discussionmentioning

confidence: 97%

Serial Diffusion-Weighted Magnetic Resonance Imaging in Methanol Intoxication

Takao

Doi²,

Watanabe³

2006

Journal of Computer Assisted Tomography

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We report the serial magnetic resonance imaging (MRI) findings in a case of methanol intoxication. A 50-year-old man who had accidentally ingested methanol was admitted to our institution. The patient was almost blind, and became comatose. The MRI showed bilateral putaminal lesions with restricted diffusion. The MRI, which was performed on the third day after admission, showed new lesions in the subcortical white matter. The patient's general condition improved. His visual acuity, however, did not improve.

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Section: Discussionmentioning

confidence: 97%

Serial Diffusion-Weighted Magnetic Resonance Imaging in Methanol Intoxication

Takao

Doi²,

Watanabe³

2006

Journal of Computer Assisted Tomography

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“…Symptoms include headache, dizziness, nausea, vomiting, abdominal pain and blurred vision. The onset of symptoms is usually delayed for 12-24 h. In severe poisoning, dyspnoea, coma, convulsion and blindness may occur41. Fatal dose can be as little as 30 ml and blindness can occur with as little as 10 ml42.…”

Section: Methanolmentioning

confidence: 99%

Illicit drugs: Effects on eye

2019

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There is a myriad of changes that can be produced in the eye by toxic drugs ranging from mild/no symptoms to severe loss of vision from endophthalmitis. The routes of administration include oral ingestion, smoking, nasal inhalation, intravenous injection, topical application or application to other mucosal surfaces. It is important to recognize certain clinical signs and symptoms in the eye produced by these toxins. This article describes in brief some of the ocular effects of commonly abused drugs. For identification of a particular poisoning, in addition to the clinical presentation, pulse, blood pressure, respiration and body temperature, pupillary size, pupillary reaction to light, ocular convergence and nystagmus can be useful indicators of the type of drug the patient is exposed to. Unmasking these features help the clinician in an early and accurate diagnosis of the offending drug as well as timely management.

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“…Severe intoxication can induce bilateral haemorrhagic necrosis of the putamen responsible for rapidonset parkinsonism [8].…”

Section: Methanol Intoxication Remains Frequent In South-eastmentioning

confidence: 99%

Methanol poisoning: two case studies of blindness in Indonesia

2011

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We report two recent cases of methanol intoxication in French patients living in Bali. These intoxications were secondary to the consumption of adulterated liquor. Both patients presented acute bilateral loss of vision a few days after methanol ingestion with no sign of recovery. The fundus showed bilateral optic atrophy that was well correlated with retinal nerve fibre layer thickness measured with spectral-domain optical coherence tomography and compatible with toxic optic neuropathy. In one of the patients, macular swelling in one eye was observed. Electroretinograms were normal contrasting with abolished visual evoked potentials. Methanol was isolated from a sample of the beverage with gas chromatography. Methanol intoxication may occur in Asia and therefore adequate information for tourists and the local population is required.

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Ocular manifestations and MRI findings in a case of methanol poisoning

Cited by 21 publications

References 8 publications

Serial Diffusion-Weighted Magnetic Resonance Imaging in Methanol Intoxication

Serial Diffusion-Weighted Magnetic Resonance Imaging in Methanol Intoxication

Illicit drugs: Effects on eye

Methanol poisoning: two case studies of blindness in Indonesia

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