Ocular Infections

Plummer, Caryn E.; Colitz, Carmen M.H.; Kuonen, V.J.

doi:10.1016/b978-1-4557-0891-8.00010-5

Cited by 2 publications

(1 citation statement)

References 70 publications

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“…Idoxuridine has also exhibited therapeutic potential against equine herpesvirus type 2 (EHV-2) by alleviating the ocular symptoms caused by the infection (Collinson et al 1994). It has also been reported that idoxuridine in the concentration of 0.1% and 0.3% trifluridine can limit the viral replication but do not kill the virus (Plummer et al 2014).…”

Section: Repurposing Of Drugsmentioning

confidence: 98%

Antivirals: Past, Present and Future

Bule

Khan

Niaz

2019

Recent Advances in Animal Virology

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The uses of antiviral agents are increasing in the new era along with the development of vaccines for the effective control of viral diseases. The main aims of antiviral agents are to minimize harm to the host system and eradicate deadly viral diseases. However, the replications of viruses in host system represent a massive therapeutic challenge than bacteria and fungi. Antiviral drugs not just penetrate to disrupt the virus' cellular divisions but also have a negative impact on normal physiological pathways in the host. Due to these issues, antiviral agents have a narrow therapeutic index than antibacterial drugs. Nephrotoxicity is the main adverse reaction of antiviral drugs in human and animals. In this chapter, we summarize the antiviral agents' past, present and future perspectives with the main focus on the brief history of antiviral in animals, miscellaneous drugs, natural products, herbal and repurposing drugs.

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Section: Repurposing Of Drugsmentioning

confidence: 98%