Ocular hypertension--a long-term follow-up of treated and untreated patients.

Abstract

SUMMARY Sixty-one patients with ocular hypertension (1 17 eyes) were followed up for I to 11 years (average 40 7 months). Ten

Visual Field Defects in Ocular Hypertension and Glaucoma

“…Thus, we would not expect all the field defects that we found in OHT using grating targets to necessarily progress to glaucomatous field de¬ fects; the 50% incidence of contrast field defects in our OHT group is considerably greater than the highest (16% to 20%) percentage of patients with OHT in whom glaucomatous field defects develop as estimated in recent prospective studies. [30][31] This work was supported by National Eye Institute grant EYO-3058 to Dr Regan and by Medical Research Council of Canada grants MA\x=req-\ 6495 and ME-7002 to Dr Regan.…”

Ocular hypertension: Correlation of anterior chamber angle width and risk of progression to glaucoma

“…Some studies have shown that lowering lOP decreases the chance of conversion to glaucoma,3D,31 but others have shown no benefit. 2,32,33,34 In the present study, no definite protective effect of tim-0101 was demonstrated against the development of visual field loss. Open angle glaucoma occurred in four timolol treated eyes, and in six control eyes in the OHOA group.…”

The Relationship between IMPS-Measured Stress Score and Intraocular Pressure among Public School Workers

“…Earlier studies have suggested that the risk of developing glaucoma is related to intraocular pressure (David et al, 1977;Armaly et al, 1980;Davanger et al, 1991;Leske et al, 1995). However, other factors are considered to play important roles in the development of open-angle glaucoma, since the overall incidence of glaucoma in patients with ocular hypertension who are followed for years has remained low, and the vast majority of patients with ocular hypertension have not exhibited pathological changes related to glaucoma (David et al, 1977;Shiose, 1990). Furthermore, a considerable portion of open-angle glaucoma patients studied had normal intraocular pressure (Shiose et al, 1991;Bonomi et al, 1998;Iwase et al, 2004).…”

“…While the pathophysiology of open-angle glaucoma, which may result in profound vision impairment if left untreated or if treated insufficiently, is not explicitly known, a number of risk factors, such as age, family history of glaucoma, diabetes mellitus, hypertension, myopia, cataracts, smoking, alcohol consumption, and stress, have been shown to be associated with open-angle glaucoma (Wilson et al, 1987;Katz and Sommer, 1988;Leske et al, 1995;Kaluza et al, 1996;Le et al, 2003;Suzuki et al, 2006). One of the most important risk factors for the development of open-angle glaucoma is elevated intraocular pressure (David et al, 1977;Seddon et al, 1983;Davanger et al, 1991;Sommer et al, 1991;Tielsch et al, 1991;Le et al, 2003;Suzuki et al, 2006), even though a considerable portion (30%) of patients with open-angle glaucoma have normal levels of intraocular pressure (Bonomi et al, 1998). Furthermore, in contrast to Western populations, the prevalence of open-angle glaucoma among patients with apparently normal intraocular pressure levels, i.e.…”