Ocular flutter following Zika virus infection

Karam, Emely; Giraldo, Jose; Rodríguez, Flor De María; Hernández‐Pereira, Carlos E.; Rodríguez‐Morales, Alfonso J.; Blohm, Gabriela M.; Paniz‐Mondolfi, Alberto

doi:10.1007/s13365-017-0585-1

Cited by 14 publications

(15 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Anterior ocular findings related to Zika virus infection include iris coloboma, cataracts, lens subluxation, intraocular calcifications and microphthalmia even in the absence of microcephaly [34,60]. However, it is known that the incidence of structural eye alterations, visual acuity loss and fundus abnormalities are significantly higher when the infected child exhibits concomitant microcephaly [14,25].…”

Section: Anterior Segment Findingsmentioning

confidence: 99%

“…Among infants with congenital Zika virus infection, the most commonly reported ocular motility disturbances include early-onset strabismus, nystagmus and ocular flutter [21,25,60]. The vascular findings are mainly subretinal hemorrhages and abnormalities in peripheral retinal vasculature, including abnormal termination of the retinal vessels, tortuosity and vascular attenuation [21].…”

Section: Ocular Motility Alterations and Vascular Findingsmentioning

confidence: 99%

See 1 more Smart Citation

The Eye and the Zika Virus

Martínez-Pulgarín¹,

Córdoba-Ortega²,

Padilla-Pantoja³

2021

Current Concepts in Zika Research

View full text Add to dashboard Cite

Ocular involvement in Zika virus (ZIKV) infection can be present both in adults and infants as acquired and congenital diseases respectively. Through experimental studies, there has been clarified important mechanisms of ocular pathogenesis that allow the establishment of potential objectives for antiviral drugs development. The spread of the virus at the ocular level could be hematogenous or axonal, however the hematogenous route through the choroid is suggested as the most important initial mechanism for infection. Ocular manifestations vary according to the age of presentation, being mild and self-limited in adults and potentially devastating in children, related to congenital Zika syndrome (CZS). Ocular diagnosis is made based in clinical features and contact/travel history to countries of epidemiological importance; fundoscopy, optical coherence tomography, fluoresceinic/green indocianine angiography, cultures, serological and molecular tests are useful diagnostic tools. Ocular management is focused according to the clinical context of each patient. Prevention is carried out in a comprehensive manner and further research is directed to vaccine development and specific antiviral treatment. Proper attention requires a multidisciplinary team in order to reach complete visual evaluation and early rehabilitation.

show abstract

Section: Anterior Segment Findingsmentioning

confidence: 99%

Section: Ocular Motility Alterations and Vascular Findingsmentioning

confidence: 99%

The Eye and the Zika Virus

Martínez-Pulgarín¹,

Córdoba-Ortega²,

Padilla-Pantoja³

2021

Current Concepts in Zika Research

View full text Add to dashboard Cite

show abstract

“…This virus was first isolated in 1947 from a monkey in the Zika forest of Uganda. Zika virus spread mainly by Aedes mosquitos as well as by intrauterine transmission, blood and sexual intercourse [20]. Most cases of Zika virus infection are associated with mild symptoms such as fever, headache, maculopapular skin rash, red eyes (conjunctivitis) and joint or muscle pain [21][22][23].…”

Section: Clinical Subtypes Of Guillain-barre Syndrome (Gbs)mentioning

confidence: 99%

Guillain-Barre Syndrome and Miller Fisher Variant in Zika Virus Disease

Jadah¹

2021

Current Concepts in Zika Research

View full text Add to dashboard Cite

Guillain-Barre syndrome (GBS) is a serious neurological disorder associated with a rapid progressive ascending muscle paralysis, and it is the most common neurological autoimmune disorder that affects the peripheral nervous system, which is usually triggered by viral or bacterial infection. GBS is rare in children and characterized by rapid progressive onset ascending muscle weakness associated with pain and sensory dysfunction. Miller Fisher syndrome (MFS), a variant of GBS, is rare in pediatric population which is typically manifested by ataxic gait, ophthalmoplegia, and areflexia since it is rare in children. It is vitally important to early diagnose this condition and to initiate early treatment to prevent further complications and long-term morbidity. Since the outbreak of Zika virus, the incidence of GBS has been increased. Zika virus associated with autoimmune anti-ganglioside antibodies trigger which lead to GBS development. Zika virus infection should be strongly considered in patients who present with classical signs of Miller Fisher syndrome, especially travelers and residents from endemic areas.

show abstract

“…The clinical spectrum of ZIKV infection remains a matter of investigation. Other manifestations have been reported such as: ocular flutter, meningoencephalitis, haematospermia, hearing difficulties, subcutaneous bleeding and acute myelitis [31,[43][44][45].…”

Section: Zika and Other Clinical Manifestations Around The Worldmentioning

confidence: 99%

Zika virus epidemiology: from Uganda to world pandemic, an update

et al. 2018

View full text Add to dashboard Cite

Zika virus (ZIKV) infection is an emergent worldwide public health problem. Historically, 84 countries have reported vector-borne ZIKV transmission, 61 of which report on-going transmission. It is a Flavivirus transmitted through arthropods belonging to the Aedes genus. Since 2015, ZIKV infections have increased dramatically; with 1.3 million people infected during 2015 in Brazil alone. This paper's objective is to highlight the conjectural epidemiological points of the virus' dissemination. The digital archives Pubmed, MEDLINE, EMBASE and Cochrane were searched for papers that assessed aspects of ZIKV transmission and epidemiology. The first isolation occurred in Uganda in 1947. Since then, important outbreaks were documented globally. Consequently, an emergent public health problem arose from a rapidly increasing incidence and its association with the development of neurological diseases such as microcephaly and Guillain-Barré syndrome. Key factors in the successful containment of outbreaks include surveillance of mosquitos in the neighbourhood, an early mosquito control treatment, an assertive information campaign, and the involvement of the local population and healthcare workers. As such, while ZIKV seems to be spreading globally in a similar manner to other arboviruses, such as Dengue and Chikungunya viruses, it can also be rapidly contained due to the pre-existing availability of necessary resources and regulatory tools as control measures. This review aims to provide a description of those characteristics of ZIKV infection that may be useful in the construction of effective outbreak control strategies.

show abstract

Ocular flutter following Zika virus infection

Cited by 14 publications

References 14 publications

The Eye and the Zika Virus

The Eye and the Zika Virus

Guillain-Barre Syndrome and Miller Fisher Variant in Zika Virus Disease

Zika virus epidemiology: from Uganda to world pandemic, an update

Contact Info

Product

Resources

About