Ocular findings in childhood-onset Behçet disease

Juvenile Adamantiades-Behçet Disease

“…Indicatively, the prevalence of JABD in France has been recorded as 1/600,000 [24]. On the other hand, in Turkey the reported results vary widely: no active ABD could be detected in a population of 46,816 children [25], while JABD prevalences of less than 0.006 [26], of 0.2 [27], of 5.3 [28] and of 13.4% [7] among all ABD patients were reported in different Turkish studies. In Germany a JABD rate of 17% among 168 ABD patients was assessed, 5% of which met the International Study Group for Behçet's Disease criteria [19] under the age of 16 [6].…”

“…Both a male [10,14,21,28,29,30] and a female [7,15,31] predominance have been registered. Overall, the male-female ratio in JABD is comparable to that in AABD [9].…”

“…The frequency of recurrent eye involvement in JABD ranges from 7.5 to 80% [9,12,13,15,16,17,21,25,26,27,28,29,30,33,35]. In a recent cohort of 3,382 ABD patients, only 3.3% were younger than 15 years, whereas 31% of the children had been diagnosed with ocular involvement [15].…”

“…Eye involvement may last for quite a few weeks. Several studies have shown that panuveitis, associated with retinal vasculitis, is the most prominent type of eye involvement [28]. The prevalence of uveitis in JABD ranges from 0.7 [37] to 14.7% [28].…”

“…Several studies have shown that panuveitis, associated with retinal vasculitis, is the most prominent type of eye involvement [28]. The prevalence of uveitis in JABD ranges from 0.7 [37] to 14.7% [28]. Further ocular manifestations include conjunctivitis, papilledema, band keratopathy, retinal vasculitis, retinitis, papillitis, macular edema, hypopyon and ophthalmomalacia [14,18,30].…”