Ocular disease-associated mutations diminish the mitotic chromosome retention ability of PAX6

Cell fate decisions, transcription factors and signaling during early retinal development

“…and 3.5 ). Recently, mitotic bookmarking of Pax6 has been demonstrated in non-ocular cultured cells ( Lan et al, 2021 ). RBPJ, the major transcriptional effector of Notch signaling, is another important bookmarking factor ( Lake et al, 2014 ).…”