Ocular demodicosis: A review

García, Viviana; Vargas, G. Valenzuela; Cornuy, M. Marín; Torres, P. Aguila

doi:10.1016/j.oftale.2019.04.001

Cited by 8 publications

(9 citation statements)

References 40 publications

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“…Demodicosis is commonly age dependent [ 11 , 14 – 16 ], with more frequent detection in individuals over 71 years old than in children between 3 and 15 years old [ 11 ]. This was consistent with the observations that demodicosis was rare in healthy children [ 11 , 17 , 18 ], and suggesting that Demodex infestation of pediatric patients is a risk factor for chalazia.…”

Section: Discussionsupporting

confidence: 92%

The association of demodex infestation with pediatric chalazia

et al. 2022

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Purpose This study aimed to investigate the association of Demodex infestation with pediatric chalazia. Methods In a prospective study, 446 children with chalazia and 50 children with non-inflammatory eye disease (controls) who underwent surgical treatment were enrolled from December 2018 to December 2019. Patient ages ranged from 7 months to 13 years old. All patients underwent eyelash sampling for light microscope examination, and statistical correlation analysis between Demodex infestation and chalazia, including the occurrence, recurrence, and course of disease, morphological characteristics, and meibomian gland dysfunction (MGD) in chalazia patients was performed. Results Demodex was found in 236 (52.91%) patients with chalazia and zero control patients. Demodicosis was significantly more prevalent in chalazia patients than the control group (P < 1 × 10− 14). Recurrent chalazia (P = 0.006) and skin surface involvement (P = 0.029) were highly correlated with Demodex infestation. Demodicosis was also associated with multiple chalazia (P = .023) and MGD(P = .024). However, Demodex infestation was comparable in the course of disease (P = 0.15), seasonal change (P = 0.68) and blepharitis subgroups (P = 0.15). Within the group of chalazia patients who underwent surgical removal of cysts, 4 (0.9%) patients with concurrent demodicosis experienced recurrence. Conclusions Demodex infestation was more prevalent in pediatric chalazia patients than healthy children, and was associated with recurrent and multiple chalazia. Demodicosis should be considered as a risk factor of chalazia. In children with chalazia, Demodex examination and comprehensive treatment of Demodex mites should be applied to potentially prevent recurrence.

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Section: Discussionsupporting

confidence: 92%

The association of demodex infestation with pediatric chalazia

et al. 2022

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“…Mites can be found in all human races around the world [ 9 , 15 , 16 , 17 , 18 ]. D. folliculorum occurs more frequently than D. brevis and infestation by both species increases with age [ 19 ]. In our study, only D. folliculorum was found in all positive samples.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Ocular Demodicosis and Ocular Surface Conditions in Patients Selected for Cataract Surgery

Nowomiejska

Łukasik

Brzozowska

et al. 2020

JCM

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The aim of the study was to analyze the prevalence of ocular demodicosis and ocular surface conditions in patients selected for cataract surgery. Eyelashes from 73 patients selected for cataract surgery were evaluated at × 40 and × 100 magnification using light microscopy. The anterior segment was assessed with the slit lamp. Additionally, Schirmer I and break up time (BUT) tests were carried out before surgery and 1 and 3 months postoperatively. A specially designed questionnaire containing e.g. information about chronic skin and eye diseases, previous ophthalmic surgeries, and patient's hygiene habits was used to assess the demographic variables. A majority of patients were at the age of 70–79 years, and there were more females (83%) in the study group. Demodex folliculorum was found in 48% of the patients. There was a correlation between the number of parasites and the presence of blepharitis, discharge at eyelid margins, and conjunctival hyperemia. Schirmer I and BUT test results were lower in patients with Demodex infestation before and after cataract surgery. The higher number of mites was correlated with lower Schirmer I test results postoperatively. The presence of Demodex mites influences the conjunctiva and lid margins leading to inflammation. The higher number of Demodex mites disturbs the tear film over time after cataract surgery.

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“…Eyelid, follicular mycosis lives in ciliated sacs. Besides, short mold lives in eyelid, eyelid gland and sebaceous gland [ 6 ]. They eat skin cells, hormones and oils from hair follicles [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease

et al. 2021

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Purpose Prevention of ocular surface (OS) Demodex infestation plays an important role in OS hygiene and variety of factors may be associated with it, in which diabetes mellitus (DM) or dry eye disease (DED) has caught the attention of most scholars. However, there has been no research on whether there was a potential interaction between DM and DED in the process of OS Demodex infestation. This cross-sectional study was implemented in Zhujiang Hospital of Southern Medical University. Methods Ophthalmologic interviews, questionnaires, and examinations were conducted. Factors including general information, DM status, dry eye condition, etc. were collected to study the correlation of DM and DED on OS Demodex infestation. Results After statistical analysis, we found that both DM (P < 0.001) and DED (P = 0.013 < 0.05) are closely associated with OS Demodex infestation. Compared with DED, DM has higher priority association with OS Demodex infestation, and patients with both diseases have a significant higher risk of OS Demodex infestation (R = 0.197, P < 0.001). Meanwhile, age (R = 0.299, P < 0.001) and hypertension (P < 0.05) were also correlated with OS Demodex infestation. Conclusion This study provides a new evidence-based basis for clinical prevention and management of OS Demodex infestation.

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Ocular demodicosis: A review

Cited by 8 publications

References 40 publications

The association of demodex infestation with pediatric chalazia

The association of demodex infestation with pediatric chalazia

Prevalence of Ocular Demodicosis and Ocular Surface Conditions in Patients Selected for Cataract Surgery

A Survey on How Ocular Surface Demodex Infestation Interactively Associates with Diabetes Mellitus and Dry Eye Disease

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