Ocular Complications in Relapsing Fever

Neuroborreliosis During Relapsing Fever: Review of the Clinical Manifestations, Pathology, and Treatment of Infections in Humans and Experimental Animals

“…Although meningismus or severe head-2 -9 weeks [30, 34, 35,42]. Occasionally the facial paralysis ache was commonly reported with LBRF, there were no reports persisted [67,68]. of CSF abnormalities in patients with this form of relapsing Involvement of other cranial nerves during TBRF was less fever.…”

“…Ocular Lumbar puncture revealed an elevated protein level in 3 of 3 patients with facial palsy and B. turicatae infections [35]. Facial disease followed a relapsing course in some cases [67,75]. Involvement of the eyes during LBRF has not been reported.…”

“…Unilateral uveitis by the same outer-membrane proteins that confer serotype specificity [106]. with gross vitreous exudate, iridocyclitis, chronic cyclitis, and persistent headache appeared in 4 (14%) of 28 cases of Relapsing-fever borrelias infect not only nervous tissue of mammalian hosts but also the comparable tissues of arthropod B. hispanica TBRF in North Africa but in none of 63 cases of B. persica TBRF in Syria [67].…”

Tickborne Relapsing Fever, Bitterroot Valley, Montana, USA

“…Various forms of uveitis have been described with other spirochetal diseases, including Lyme disease ( 23 ), syphilis ( 24 ), and leptospirosis ( 25 ). Ocular complications, including uveitis, have been reported for cases of relapsing fever caused by other species of spirochetes ( 16 ), such as in troops in Libya during World War II ( 26 ). Iritis (anterior uveitis) has been associated with a few cases of relapsing fever in the southwestern United States ( 27 ), which were probably caused by B. turicatae .…”

Treatment of Relapsing Fever With Antibiotics

“…The extent to which central nervous system involvement occurs in man is not established. Numerous recent investigators, however, have reported nervous manifestations in some or all of their cases of relapsing fever {Hawking, 1941;Hamilton, 1943;Marques, 1943;Scott, 1944;Cattan, Corcos, and Cohen, 1945;Taft and Pike, 1945;Renaud and Regullo, 1946;Aubin, Gachkel, and Gallo, 1947;Bergeret and Raoult, 1948;Heisch, 1950). In contrast to these, Narain and Kalra (1950) report that their Kashmir (India) cases of relapsing fever rarely tend to show evidence of central nervous system involvement.…”