Ocular blood flow in diabetes and age-related macular degeneration

Assessment of Retinal and Choroidal Blood Flow Changes Using Laser Doppler Flowmetry in Rats

“…[3][4][5] An understanding of the hemodynamic mechanisms generated during retinal damage is essential for the development of new therapeutic avenues. Laser Doppler flowmetry (LDF) is used to assess ocular blood flow in the clinical setting.…”

Diabetes Mellitus and Glaucoma

“…Over a period of up to 4 years, PERG waveforms were reduced significantly in patients with diabetes and OHT compared with normal control subjects with normal vision. First, vascular autoregulation is altered in both diabetes 43 and glaucoma, 44 possibly related to autonomic dysfunction or local vasoactive agents such as nitric oxide. The mean PERG amplitude of diabetic glaucoma subjects without retinopathy was significantly smaller (P < 0.05) than that of nondiabetic glaucoma subjects after adjustment for individual differences in age, visual acuity, visual field defect, and IOP.…”

Method comparison of two non‐invasive dual‐wavelength spectrophotometric retinal oximeters in healthy young subjects during normoxia

“…Non-invasive retinal oximetry was already used in health (Yang et al 2016;Liu et al 2017) and disease and has gained interest because various eye diseases such as diabetic retinopathy, glaucoma or CRVO are associated with changes in retinal oxygenation and perfusion, which may lead to hypoxia (Pemp & Schmetterer 2008;Hammer et al 2009;Olafsdottir et al 2014; Vandewalle et al 2014;Rilven et al 2017).…”