Ocular blood-flow hemodynamics before and after application of a laser in situ keratomileusis ring

Conway, Miriam L.; Wevill, Mark; Benavente-Perez, Alexandra; Hosking, Sarah

doi:10.1016/j.jcrs.2009.09.013

Cited by 37 publications

(24 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This could be a result of IOP increased beyond perfusion pressure. As a result, ocular blood flow might be reduced below a critical level, 17,18 or possibly direct transient stress to the optic nerve fibers in the lamina cribrosa might cause the sensations reported by the patients.…”

Section: Discussionmentioning

confidence: 99%

Profiles of Intraocular Pressure in Human Donor Eyes during Femtosecond Laser Procedures—A Comparative Study

Strohmaier¹,

Runge²,

Seyeddain³

et al. 2013

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Profiles of Intraocular Pressure in Human Donor Eyes during Femtosecond Laser Procedures—A Comparative Study

Strohmaier¹,

Runge²,

Seyeddain³

et al. 2013

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

“…However, the increase in the slope of the regression line (becoming more negative) with increasing ODF as seen in Figs 7 and 8 and the negative values in the interaction terms in Eqs 13 and 14 involve complex hemodynamic mechanisms, which are poorly understood. Theoretical [91] and experimental models [92][93][94] have attempted to investigate the retinal and retrobulbar hemodynamic changes from induced IOP elevation. Harris et al using color doppler imaging, reported changes in the central retinal artery (CRA) including reduced peak systolic velocity, end-diastolic velocity and an increase in the resistive index.…”

Section: Plos Onementioning

confidence: 99%

Measurement of normal retinal vascular pulse wave attenuation using modified photoplethysmography

Abdul-Rahman

Morgan

2020

PLoS ONE

View full text Add to dashboard Cite

Pulse wave attenuation characteristics reflect compliance and resistance properties of the vessel wall as well as initial pulse generation factors. Recently, it has become possible to measure and map the retinal vessel wall pulse wave amplitudes. Predictable pulse wave amplitude distribution may allow inferences to be made concerning vascular compliance and resistance. Twenty-eight eyes from sixteen subjects (8 male and 8 female) were examined using modified retinal photoplethysmography with simultaneous ophthalmodynamometry. This allowed the assessment of vessel wall pulsation amplitudes under a dynamic range of intraocular pressures. Pulse amplitudes were calculated using harmonic regression analysis. The pulse wave attenuation was measured under different ranges of ophthalmodynamometric force (ODF) as a function of distance along the vessel (V Dist ), which in turn was calculated in disc diameters (DD) from the center of the optic disc. A linear mixed-effects model with randomized slopes and intercepts was used to estimate the correlations between the logarithmically transformed harmonic regression wave amplitude (HRW a ) and the Fourier trigonometric coefficients with the predictors (V Dist and ODF). The retinal venous harmonic regression wave attenuation (coefficient value±standard error) -0.40±0.065/DD, (p-value < 0.00001, 95% confidence interval (CI) -0.53 to -0.27), which was approximately twice that of the arterial -0.17±0.048/DD, (p-value < 0.0004, 95% CI = -0.27 to -0.08). There was a positive correlation between attenuation of the harmonic regression wave and ophthalmodynamometric force in both vascular systems. The attenuation of all but the sine coefficient of the second Fourier harmonic (b n2 ) achieved statistical significance in the correlation with V Dist . The cosine coefficient of the first Fourier harmonic a n1 was the only coefficient to achieve statistical significance in the correlation with the predictors V Dist and ODF in both vascular systems. The a n1 coefficient value in the correlation with V Dist was -3.79±0.78 and -1.269±0.37 (p < 0.0006), while this coefficient value in the correlation with ODF was 0.026±0.0099 and 0.009±0.04 (p < 0.01) in both the retinal veins and arteries respectively. The predictable attenuation characteristics in normal subjects suggest that this technique may allow the non-invasive quantification of retinal vascular compliance and other hemodynamic parameters.

show abstract

“…One hypothesis is that application of a microkeratome induces IOP increases up to 90 mm Hg and changes the shape of the eye. [24][25][26][27] The anterior segment is drawn into a vacuum chamber, and the eye elongates along the anteroposterior axis. Because the globe is a closed system, the eye must contract along the horizontal axis.…”

Section: Discussionmentioning

confidence: 99%

Occurrence of posterior vitreous detachment after femtosecond laser in situ keratomileusis: Ultrasound evaluation

Gavrilov¹,

Gaujoux²,

Sellam³

et al. 2011

Journal of Cataract and Refractive Surgery

View full text Add to dashboard Cite

show abstract

Ocular blood-flow hemodynamics before and after application of a laser in situ keratomileusis ring

Abstract: In normal healthy eyes, once suction was released, blood-flow responses returned immediately to normal levels.

Cited by 37 publications

References 30 publications

Profiles of Intraocular Pressure in Human Donor Eyes during Femtosecond Laser Procedures—A Comparative Study

Profiles of Intraocular Pressure in Human Donor Eyes during Femtosecond Laser Procedures—A Comparative Study

Measurement of normal retinal vascular pulse wave attenuation using modified photoplethysmography

Occurrence of posterior vitreous detachment after femtosecond laser in situ keratomileusis: Ultrasound evaluation

Contact Info

Product

Resources

About