Ocular allergies

Messmer, Elisabeth M.

doi:10.1007/s00347-005-1181-y

Cited by 12 publications

(9 citation statements)

References 121 publications

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“…AC ranges from more prevalent non-sight threatening conditions like seasonal allergic conjunctivitis (SAC), perennial allergic conjunctivitis (PAC) and giant papillary conjunctivitis (GPC) to less prevalent sight-threatening ones such as vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC) [ 4 ]. Generally, it is a type 1 immunoglobulin E (IgE) mediated hypersensitivity reaction while cell-mediated T-helper cells-2 (Th-2) are implicated in some types [ 4 , 5 ]. AC involves a cascade of events which begins when mast cells become unstable and subsequently break down [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…The process could be heightened and become chronic in nature with progressive recruitment of neutrophils and eosinophils by mast-cell derived cytokines and Th-2 cytokines respectively [ 8 , 9 ]. This is what leads to a probable development of papillae in some patients [ 5 ]. It is difficult finding a single cause for AC because it is believed to result from an interplay of varying causative factors like genetics, air pollution in urban areas, pets, warmer climates and early childhood exposure [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence of allergic conjunctivitis among basic school children in the Kumasi Metropolis (Ghana): a community-based cross-sectional study

et al. 2015

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BackgroundThere seems a preponderance of hospital-based studies on the prevalence of Allergic Conjunctivitis (AC) compared to community-based ones, particularly among children in Ghana and Africa as a whole. Meanwhile, literature supports the possibility of underdiagnosing AC in the hospital setting; exponentially so when males generally have poor hospital-attending behavior. This may lead to underestimation of the true burden of AC. Consequently, the purpose of the current community-based study was to determine the prevalence of AC among basic school children in the Kumasi Metropolis, while identifying its associated symptoms.MethodsA cross-sectional community-based study involving 1571 students from 11 basic schools (Primary and JHS) participated in the study. Data collection started in November 2011 and was completed in March 2014. After history taking, subjects underwent a battery of tests; visual acuity, objective refraction, anterior and posterior segments examination with a slit-lamp and a direct ophthalmoscope respectively.ResultsThe prevalence of AC was 39.9 %. The mean (±SD) age of participants was 8 ± 0.65 years. AC was significantly associated with gender (p < 0.05), but not with age (p > 0.05). A total of 70 % of the students with AC never had any form of treatment.ConclusionsAC is an endemic ocular disease among basic schools in the Kumasi metropolis and therefore calls for pragmatic and proactive measures to reduce its burden and effects on its victims. Public health measures may be required to help reduce the burden associated with this condition.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prevalence of allergic conjunctivitis among basic school children in the Kumasi Metropolis (Ghana): a community-based cross-sectional study

et al. 2015

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“…These mast cell-derived cytokines also recruit neutrophils and TH2 cytokines recruit eosinophils promoting increased sensitivity. This process could then progress to chronic allergic inflammation567 where there is proliferation of fibroblast in the conjunctiva with resultant development of papillae in some patients 89…”

Section: Introductionmentioning

confidence: 99%

“…There are also climatic and racial risk factors involved in some types of AC. It is more prevalent in warm climatic conditions and more among Afro- Caribbeans, Arabs and Asians and less among the white population 567810111213. The prevalence seems to be declining among the Caucasians.…”

Section: Introductionmentioning

confidence: 99%

Allergic conjunctivitis in Jos-Nigeria

Malu

2014

Niger Med J

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Background:Allergic conjunctivitis (AC) may follow seasonal or perennial pattern. There are climatic and racial risk factors involved in some types of AC. It is more prevalent in warm climatic conditions and among Afro-Caribbeans, Arabs and Asians and less among the White populations. Clinical presentations also seem to follow climatic and genetic predisposition. The purpose of this study is to determine the prevalence of AC and its clinical presentations in a hospital setting in this region in people of all ages.Materials and Methods:This is a hospital-based retrospective study of new patients seen at Adoose Specialist Hospital, Jos the capital city of Plateau State in North Central Nigeria with clinical diagnosis of AC from 2000 to 2009.Results:There were 972 subjects, 474 (48.8%) males and 498 (51.2%) females with M:F ratio of 1:1.05. The most common symptom was itching followed by redness, pains, watery/mucoid discharge, sticky eyes, puffy eyes and photophobia. The presence of papillae in the upper tarsal or lower conjunctiva, a discrete or confluent gelatinous hypertrophy of the limbal conjunctiva (Trantas dots), hyperpigmentation, hyperemia/chemosis of the conjunctiva were the common signs. AC was more prevalent in those aged 1−16 years 38.4% decreasing to 4.9% in the age group above 50 years. The presentation followed perennial pattern, with a peak around July. The most prevalent ocular comorbid condition was refractive error (distant RE and presbyopia) in 15.4%, followed by pterygium/pinguecula 3.6%, bacterial conjunctivitis in 2.2%, glaucoma 2.1% and eyelid disorders 1.7%. Cataract was present in 1.3%, and keratopathy 1.1%. Other conditions such as episcleritis, dry eye, vitamin A deficiency and posterior segment disease were also present in decreasing order. Systemic association were few with generalised body atopy in 0.3%.Conclusion:The prevalence of AC was 32% and is similar to what pertains in some of the African hospital studies, but differs in presentation from the Caucasians.

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“…Fumarato de cetotifeno, além das ações já descritas para olopatadina, é também inibidor de migração de eosinófilos (3,5,9) .…”

Section: Resumo No Tratamento Da Ceratoconjuntivite Primaverilunclassified

Comparação entre o uso tópico do fumarato de cetotifeno 0,025% e do cloridrato de olopatadina 0,1% no tratamento da ceratoconjuntivite primaveril

Hida¹,

Nogueira²,

Schaefer³

et al. 2006

Arq. Bras. Oftalmol.

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Ocular allergies

Cited by 12 publications

References 121 publications

Prevalence of allergic conjunctivitis among basic school children in the Kumasi Metropolis (Ghana): a community-based cross-sectional study

Prevalence of allergic conjunctivitis among basic school children in the Kumasi Metropolis (Ghana): a community-based cross-sectional study

Allergic conjunctivitis in Jos-Nigeria

Comparação entre o uso tópico do fumarato de cetotifeno 0,025% e do cloridrato de olopatadina 0,1% no tratamento da ceratoconjuntivite primaveril

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